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Tweek

A character from the T.V show "South Park". He has very messy blonde hair and supposedly sufferes from A.D.D but his twitching and nervous personality is due to the large amounts of caffeine he consumes. In Series 6, Tweek became the main characters replacement for Kenny, alongside Butters, after he "permeanantly" died at the end of the previous series.
"Tweek's the worst character ever."
"Yeah. Worse than Towelie."
by Issy Aidsfunop January 22, 2006
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tweek

to be overly excited at a situation or event that is highly positive and causes exuberance beyond classification of excitement.
Scott won a vacation to Hawaii, a place he always wanted to go, causing him to call his friends and tweek.
by BT14 August 3, 2007
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Hypno-tweek

The act of falling asleep and then spasming awake to try and stay awake.

The action in which ones body twitches apon the verge of sleep
John: Get off my computer!
Jim: Gimme 5 minutes
(5 minutes later
John Passed out)
John Spasmed
Jim: DUDE you hypno-tweeked
John: I Thought i was falling...
by Minecrafter 666 November 17, 2011
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Tweek Trap

A huge scary pile of precariously balanced clutter that is unconsciously created by a tweeker while conducting a desperate search for that bag of dope they think they lost somewhere. A real-life version of Jenga.
I went to Todd's room in the Tenderloin to borrow a bike tool, but when he reached in to grab it, his entire tweek trap came crashing down, leading to extensive injuries. But he found his bag!
by Null Iffy November 28, 2011
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Tweek

To pinch or flick...
"I tweeked her nipple and she tweeked my clit with her tongue."
by Junebug December 28, 2005
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tweek-a-boo

When someone repeatedly peeks their head out of windows, curtains or blinds, from doorways, furnature, hallways, or just about any object they can hide behind, while high on Meth This can go on for days even weeks at a time, some will even take turns or rotate watch amungst themselves!
RIchard has been poppin his head out the door everytime a car drives by since YEsterday morning Suzy's been doin the same since that evening! Must be a really great game of Tweek-a-boo they are having!!
by JUST IN YA April 18, 2011
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Tweek

A smol chubby talented gay babey.
Appears on southpark. He's addicted to coffee and meth, and loves to play the piano. He's a good singer.
He and Craig Tucker are a couple. Like I said earlier, he gae.
TweekXCraig is my favorite episode!they were so gay in it! Especially Tweek!
by The_emo_bunny_ August 9, 2019
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