This expression is supposed to imply a juxtaposition of a crass or offensive action against something that is held as sacrosanct by someone else.
Coined by Ben "Yahtzee" Croshaw
Coined by Ben "Yahtzee" Croshaw
"For four, what the fuck happened to Clive Winston, you pricks?! In his place we've got some multicoloured, giggly J-pop creature, and you can't play classic rock with that...thing. It's like cock-slapping the Mona Lisa."
-Ben "Yahtzee" Croshaw in his Guitar Hero III review
-Ben "Yahtzee" Croshaw in his Guitar Hero III review
by Platitude May 27, 2015
Get the Cock-Slapping the Mona Lisamug. A sex act when a young "artist" tricks an old dirty art teacher into holding up a empty picture frame. He then shoots "patronage" (i.e. semen) all over her face through the frame, and earns his A.
by SukyPirate November 16, 2009
Get the The ol' Mona Lisa Twistmug. 
The artful splatter left on the back of the toilet bowl from explosive diarrhea. Almost like a fecal Rorschach test.
Man, that girl from the party last night got the green apple splatters and left a wicked mona lisa in my toilet. It's very impressive, but i wont be calling her back.
by mr.self.destruct December 13, 2022
Get the Mona Lisamug. A “Mona Lisa” is an extremely beautiful girl that is used to break down the defenses of your opposition to ether set them up or for her cause a form of harm to them. Explained in Lil Wayne- Mona Lisa
by King ADG April 8, 2022
Get the Mona Lisamug. When a cleavage looks kind of perky and happy but also a little on the sad any unperky side at the same time.
"Have you seen Emily's breasts? Her tits are like "Wow!" but also kind of "Meh." at the same time... I feel like her cleavage is somehow smiling at me--but also frowning at me! It's like she's got that whole Mona Lisa Cleavage thing going on. You know, like auntie Sara."
by Turtleboy3000 September 19, 2016
Get the Mona Lisa cleavagemug. 