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mcDonald's 

A shitty, unhealthy fastfood restaurant that most Americans love to eat. The biggest fastfood franchise in the world. The spread of McDonald's in other countries also symbolizes the spread of American way of thinking, that is rationally break down things into standard procedures.
McDonald's burger has shit in it.
McDonaldization is a world-wide cultural invasion.
mcDonald's by Kythdsifek July 9, 2005

i'd hit it like a mcdonald's cheeseburger 

To have sex with (see "I'd hit it.")

Essentially making fun of the McDonald's commercial that uses "I'd hit it" with reference to a cheeseburger, which everyone knows is utterly misguided.
Wow look at that ass!
I'd hit it like a McDonald's cheeseburger.

McDonald's 

A restaurant chain that shamelessly whores itself to minorities, and evidenced by their latest "Ba-da-ba-ba-ba...I'm luvin'it!" campaign. The food is terrible with the exception of the fries, McChicken sandwich, and McFlurry.

Probably laces the food with nicotine.
As the last french fry disappeared forever beyond her event horizon, Sally accidentally saw her reflection in the window and shuddered at what she'd become. At that moment she realized there was only one logical course of action: she had to sue McDonald's.
McDonald's by Veldrimal December 14, 2004

McDonald's 

The source of all obesity in the world. The reason the United States has such a problem with being fit. They serve the absolute shittiest excuse for "food" and expect you to pay for it. "Big Mac" is their signature piece of shit on the menu, among other shit that they claim is now "healthier", but really isn't at all. Basically, if you eat there you are bound for a life of obesity and other health problems.
Guy 1: "Hey man its time for lunch; Want to go to McDonald's?"
Guy 2: "Hell no, man that place is shit. If you go there, that's pretty much suicide by junk "food".

Guy 1: "But I'm really hungry!"
Guy 2: "OK, but don't say I didn't warn you!"
(1/2 hour later guy 1 gets a call at the office saying that guy 2 died of a heart attack 3 bites into his first BIG MAC.)
McDonald's by BIGRED1313 November 7, 2011

McDonald's Happy Meal 

When you take a quarter pound cheeseburger, milkshake, fries, diced apples, and a toy, and shove it up an pussy and fuck it. After, you and your partner can enjoy a McDonald's Happy Meal
I served Jessica the McDonald's Happy Meal so hard she passed out.

mcdonald's 

The birthplace of pickle wars and chicken nugget hockey.
"Wayne Gretsky started his hockey career sweeping nuggets into the dustpan at McDonald's."
mcdonald's by Kris-10 April 27, 2005