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A HUMAN SKIDMARK ON THE UNDERWEAR OF LIFE 

A contemptible and low-life individual;
a person who's a waste of oxygen and flesh; the ultimate scumbag of existence!
Pete's wife aptly labeled him as a "human skidmark on the underwear of life" when he forgot to acknowledge their 20th wedding anniversary by having an illicit fling with the baby-sitter at the local hotel.
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Human Cow 

A lactating female who allows herself to have her jugs hooked up to a cow milking machine, usually wearing a cow mask and cow print leather chaps.
That guy's girlfriend is a human cow! He milks her...literally.
Human Cow by Trish54 February 9, 2009

human bean 

A sympathetic but emotionless bean-eater that has seen all the goods and bads in humanity, and is willing to make sacrifice(s) to fulfil something that is greater than the value he or she places on himself/herself because of a strong sympathy on other beings.
human bean by HY371c May 3, 2018

Cards Against Humanity 

What are you going to put in there?

"Cards Against Humanity." If you know what I mean.

human thumb 

This guy was made famous around the web after he got pictured looking literally like a thumb.
This is actually amazing, just google image it.
Used sometimes when one of your friend looks like him on a picture, or to describe any fat bold guy.
Never heard of the human thumb? Check him out, this guy's awesome.
Haha you look like the human thumb on this picture!
human thumb by B.P.O. April 13, 2011

AP Human 

Short for "Advanced Placement Human Geography", usually used when asking friends about something /bitching about the class. Generally an easy course as long as you don't sleep during the lecture and read the book.
"Dude, do you have the notes for AP Human?"

"Naw, she was going too fast so I just sat there and fantasized about Alexi Laiho."