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Little chromo syndrome

When a man is being annoying, rude, angry, or grumpy he's got "little chromo syndrome" because the Y chromosome is tiny compared to the X.
"oh god, he's totally got little chromo syndrome"
by Chromohomo July 14, 2022
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Little Bitch

US Senator from Missouri Josh Hawely.
He tried to act hard with his fist bump, but that little bitch ran as fast as he could from the insurrection.
by PoliticalObserver July 22, 2022
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Little wag

Two trays dog sidekick who's favorite toy is an empty plastic bottle and if were a human would 100% have asthma

He’s also two trays favorite kid
Two trays: come on little wag let’s roll out

Little wag: *excessive wheezing breath*
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Little Miss

An unbearable Instagram trend that is used to make basic girls feel quirky and different by doing mundane things that everyone else does like drinking iced coffee and petting their dog.
“Little miss drink iced coffee and make stomach hurt”

“Please shut the hell up
by Kingbrody July 27, 2022
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little shot focker

little five year old in call of duty lobby
P1: Where is the little shot focker?
P2: He's behind you
P1: *turns around* *little shot focker has a knife*
P2: SHI-
by The Ducko July 27, 2022
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little shot focker

five year old in call of duty lobby
P1: where is the little shot focker?
P2: behind you
P1: turns around he is holding knife
P2: SHI-
by The Ducko July 27, 2022
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Acting like a little devil worshipper

When someone starts to question their religious faith or attending church services.
Kim: You going to Sunday Service next week?
Denise: I don't go to church anymore. I don't really believe in Jesus and all that anymore...
Kim: You acting like a little devil worshipper now. You need to go to church, girl.
by Chrrrruch July 28, 2022
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