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The word is used multiple times in the Harry Potter series.

Those who do not contain any magical blood.
Two wizards trying to open a door:

A: "I can't open that door!"
B: "Are you a muggle or what? Use your wand!"
muggle by MuggleLuver April 29, 2009
A term that IT Professionals use to refer to a 'user'. This indicates that users have no magical 'IT' powers and that the support team are a group of wizards.
IT guy - "Omg, I can't believe this guy. I walked down 3 flights of stairs just to find out that the muggle had forgotten to switch his monitor on."
Muggle by Lord Canterbury October 2, 2014
When someone robs you but then hugs you for awhile before running away
I got muggled today! He got my money, but he hugged me so I don't feel too bad.
Muggle by Aly3277 February 15, 2010
Mike: Your brother is hot, Michelle! Michelle: Dude, he's not gay; he's a muggle.
Muggle by PSrz March 17, 2010
A COMPLETELY Racist remark aganist those without magical skills! Muggles are people without magical abilities, and "wizards" refer to them as such, completely racist! G-Unit
"Muggles, are basically, everyday humans."
Muggle by Uncle Vernon September 2, 2005
Someone who does not have the ability to conduct magical powers. Is not skilled with a wand or with spells
A NON- Wizard, A muggle