iss 

they are amazing kind and nice and a lot of people like them

girl 1:have you seen the new boy
girl 1:he such a iss
girl 2:yea

iss by among.us October 3, 2021

iss 

they are a nice kind and loyal person and popular but they do get stubborn

girl 1:have you seen the new boy

girl 1:he such a iss
girl 2:yea

iss by among.us October 3, 2021

Iss 

A Common Bengali Expression To Show Disgust

"Iss, he didnt wash his hands before eating"

Iss by UrBangaliBoy August 10, 2022

ISS 

In-School suspension. What i'm in right now cause of this racist ass school for thinking i instagated between these 2 people that had a problem

Friend 1: Why werent you in class the whole day?
Me: Sorry I was in ISS.

ISS by Your Pseodonym: February 6, 2023

ISS 

The act of Docking while participating and achieving the mile high club.

“Did you get to join the Mike high club?”

“Yeah man, but me and him made the ISS”

ISS by Fatherless Behavior August 26, 2025

Iss Afto 

Mrs. Afton.....your a FNaF fan?? ( ͡° ͜ʖ ͡°)

Hey guys look! It’s William’s ex/wife! Iss Afto

Iss Afto by Ilikecheeseheheheheheh May 20, 2021

iss-iss 

An exclamation of delight or bliss, when in a particular comfortable or cosy environment.

(Following a rigid and exhausting day. Showered and slipping between freshly laundered and warm bedclothes) "Iss-Iss!"

iss-iss by chris wheelie April 30, 2005