tweek 

Generally used as a verb to refer to what a DJ does to the knobs on the mixer.

Did you see that DJ tweek the knobs?
Tweekin' the knobs!

tweek by katze April 19, 2005

Tweek 

A mad individual who can cause pain to himself and not give a damn. the spawn of god and satan.

Will act as below:

Runs around fields on cold night, in only his underwear, smoking and screaming "I rape chickens". sleep talks about foursoms, chickens, wanting sausages, and aaarrghffejwfbisduf!!

Tweek by Ernie October 15, 2004

Tweek 

to pinch or flick

I tweeked her nipple and she tweeked my clit with her tongue.

Tweek by Junebug January 13, 2004

tweek 

something that looks strange or is very cool

dude that shit is tweek!

tweek by steakman1 February 12, 2007

Tweek 

To Tweek is to be overly excited about something, or keep talking about it or just plain out being anoyying about that topic.

Jay: Norman! Stop tweeking over them damn books man!

Norman: But man they're so good like in chapter 3- "Blah blah blah blah blah blah blah blah blah blah blah blah blah blah blah blah"

Jay: DUDE STOP TWEEKIN!

Tweek by Definition Queen June 7, 2009

tweek 

Something or someone that is stupid, dumb, or crazy.

"Stop being such a tweek !"

Person#1: I failed the history test.
Person#2: That was so easy, you tweek !

tweek by kimbop October 3, 2009

tweek 

to be messed up

"Man my arm is totally tweeked..."

tweek by kevsgrl2004 June 9, 2003