Rufio: Hey what's up?
Scy: Nothing much you?
Lou: Well I got a PS3.
Tad: Well...actually I just bought something better... the SEXBOX 360.
Scy: Nothing much you?
Lou: Well I got a PS3.
Tad: Well...actually I just bought something better... the SEXBOX 360.
by Smartkidz February 21, 2009
Get the SexBox 360 mug.Where a guy simply dunks his junk in the disc tray of an Xbox and proceeds to open and close it repeatedly.
"What the fuck man, my disc tray won't close properly!"
..."Oh yeah I totally seXboxed it last night."
..."Oh yeah I totally seXboxed it last night."
by Still Searching November 5, 2008
Get the SeXbox mug.Related Words
suxbox
• sexbox
• Suboxone
• SeXBOXing
• Sexbox 369
• SexBoxed
• Sexbox Sunday
• subbox
• subox
• Suboxatalk
Suboxone is the trade name for a medication that contains buprenorphine and naloxone. A very similar medication, Subutex, contains buprenorphine without naloxone. Both are manufactured and sold by a British company, Reckitt-Benckiser, and are scheduled to lose their patent protection in 2009. Both medications are indicated for treatment of opiate dependence, and both are also used 'off label' to treat chronic pain.
The active substance, buprenorphine, has effects at the mu opiate receptor that are different than effects of pain pills or methadone. Oxycodone, methadone, and hydrocodone are all 'agonists', meaning that the more drug, the more effect at the receptor. Naloxone and Naltrexone are mu 'antagonists'-- they will block the effects of pain pills and have no stimulating effect at the receptor. Buprenorphine is a 'partial agonist'-- in between the two. It will activate the mu receptor and relieve pain up to a certain point, where it has a 'ceiling' to it's effect. Beyond that point, any increases in dose of buprenorphine will have no extra effect. Buprenorphine becomes an 'antagonist' at that point, blocking the receptor so that any other opiate medications will be ineffective.
The result is that treatment with buprenorphine virtually eliminates cravings for opiates in opiate addicts who use it properly. It can be taken once per day, and will also block the effects of any other opiates the addict may take. Because of these effects, buprenorphine is considered a 'remission agent'-- it will induce remission of opiate addiction, but it is NOT a cure. When an addict stops buprenorphine, all of the prior features of his/her addiction will return if the addict does not do something to replace the buprenorphine-- such as become involved in 12 step groups.
While not a cure, there is no truth to the oft-heard comment that buprenorphine is only 'replacing one drug with another'. Opiate addiction consists of the obsession for opiates; the addict's mind is taken over by the singular concern for finding the next dose. Buprenorphine effectively treats addiction by eliminating the obsession far beyond what occurs with taking an opiate agonist.
More and more addictionologists are recognizing that buprenorphine and Suboxone should be considered long term treatments.
The active substance, buprenorphine, has effects at the mu opiate receptor that are different than effects of pain pills or methadone. Oxycodone, methadone, and hydrocodone are all 'agonists', meaning that the more drug, the more effect at the receptor. Naloxone and Naltrexone are mu 'antagonists'-- they will block the effects of pain pills and have no stimulating effect at the receptor. Buprenorphine is a 'partial agonist'-- in between the two. It will activate the mu receptor and relieve pain up to a certain point, where it has a 'ceiling' to it's effect. Beyond that point, any increases in dose of buprenorphine will have no extra effect. Buprenorphine becomes an 'antagonist' at that point, blocking the receptor so that any other opiate medications will be ineffective.
The result is that treatment with buprenorphine virtually eliminates cravings for opiates in opiate addicts who use it properly. It can be taken once per day, and will also block the effects of any other opiates the addict may take. Because of these effects, buprenorphine is considered a 'remission agent'-- it will induce remission of opiate addiction, but it is NOT a cure. When an addict stops buprenorphine, all of the prior features of his/her addiction will return if the addict does not do something to replace the buprenorphine-- such as become involved in 12 step groups.
While not a cure, there is no truth to the oft-heard comment that buprenorphine is only 'replacing one drug with another'. Opiate addiction consists of the obsession for opiates; the addict's mind is taken over by the singular concern for finding the next dose. Buprenorphine effectively treats addiction by eliminating the obsession far beyond what occurs with taking an opiate agonist.
More and more addictionologists are recognizing that buprenorphine and Suboxone should be considered long term treatments.
I am sick and tired of chasing after 'contins, so I'm going to find a doc certified to treat me with Suboxone.
by SuboxDoc December 15, 2008
Get the Suboxone mug.1. (noun) An alternate name for the Xbox.
2. (verb) When a person you are dating or otherwise hooking up with (usually male) invites you over under the guise of playing video games and/or watching movies, but implicitly for the purpose of hooking up.
2. (verb) When a person you are dating or otherwise hooking up with (usually male) invites you over under the guise of playing video games and/or watching movies, but implicitly for the purpose of hooking up.
1. "I spent most of winter vacation holed up in my apartment playing some seXbox; it was lame."
2. "Whatever happened to you and that Ryan guy?"
"We used to go out sometimes, but after a while he was just seXboxing me and I stopped going over to his place to 'hang out.'"
2. "Whatever happened to you and that Ryan guy?"
"We used to go out sometimes, but after a while he was just seXboxing me and I stopped going over to his place to 'hang out.'"
by K. Kapow August 29, 2009
Get the seXbox mug.The suboxone can only be properly dosed if you are smack dab in the middle of your withdrawal, so the doctors can see the level of dependence. They say stop taking everything 48-72 hours before your appointment. You should be dosed right there in the office that day. I have had many friends with success but some had relapses too because if you stop your suboxone therapy too soon the craving returns as intense as before the treatment. We all have our struggles and demons. If you're reading this considering suboxone therapy, please know you're not alone. I start in two weeks. I'm scared, but I'm ready.
I am spending way too much money on these pills, but I can't stop by myself. Maybe I'll try suboxone therapy.
by ellam71106 May 12, 2009
Get the Suboxone mug.SEXBOX 369
(Use just Sexbox when using it as a noun)Hey dude I just got some great Sexbox from Kali McGraw last night.
(Use 369 when using it as a verb)Kali McGraw 369ed me last night in the back of your car.
(Use just Sexbox when using it as a noun)Hey dude I just got some great Sexbox from Kali McGraw last night.
(Use 369 when using it as a verb)Kali McGraw 369ed me last night in the back of your car.
by Big Sillay and Big Ellay December 18, 2008
Get the Sexbox 369 mug.Suboxone is a medication that was approved in 2000 to treat opioid/heroin dependence. It contains the medication Buprenorphine which is a medication that blocks other opiates from reaching the receptors in your brain (basically saying that if you take a Suboxone you can not get "high" from heroin or any other opiates). Suboxone also contains a medication containing Naloxone. Naloxone is used to reverse overdoses of opiates. Naloxone does not interfere with buprenorphine's effects when Suboxone is taken sublingually (dissolving under your tounge) as prescribed. The naloxone is there to deter people from dissolving Suboxone and injecting it, b/c the naloxone can cause severe withdrawal symptoms very rapidly. Suboxone comes in 8mg & 2mg strengths. They are stop sign shaped and are orange and taste like lemon-lime. There is also Subutex which is only buprenorphine, w/o naloxone and these may be used to start people on treatment for opioid dependency.
by chloe84 February 5, 2010
Get the Suboxone mug.