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A drug you do when you're out of all your other drugs.
"Now that all my good shit is gone, I guess I'll holla at some Suboxone."
by Go-Go16 April 29, 2013
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May 8 Word of the Day
1. Slight sins or offenses
2. Petty crimes or small infractions
3. Las Vegas Punk Rock!
Peccadilloes shows rule.
by James Messina August 11, 2006
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Suboxone is the trade name for a medication that contains buprenorphine and naloxone. A very similar medication, Subutex, contains buprenorphine without naloxone. Both are manufactured and sold by a British company, Reckitt-Benckiser, and are scheduled to lose their patent protection in 2009. Both medications are indicated for treatment of opiate dependence, and both are also used 'off label' to treat chronic pain.

The active substance, buprenorphine, has effects at the mu opiate receptor that are different than effects of pain pills or methadone. Oxycodone, methadone, and hydrocodone are all 'agonists', meaning that the more drug, the more effect at the receptor. Naloxone and Naltrexone are mu 'antagonists'-- they will block the effects of pain pills and have no stimulating effect at the receptor. Buprenorphine is a 'partial agonist'-- in between the two. It will activate the mu receptor and relieve pain up to a certain point, where it has a 'ceiling' to it's effect. Beyond that point, any increases in dose of buprenorphine will have no extra effect. Buprenorphine becomes an 'antagonist' at that point, blocking the receptor so that any other opiate medications will be ineffective.

The result is that treatment with buprenorphine virtually eliminates cravings for opiates in opiate addicts who use it properly. It can be taken once per day, and will also block the effects of any other opiates the addict may take. Because of these effects, buprenorphine is considered a 'remission agent'-- it will induce remission of opiate addiction, but it is NOT a cure. When an addict stops buprenorphine, all of the prior features of his/her addiction will return if the addict does not do something to replace the buprenorphine-- such as become involved in 12 step groups.

While not a cure, there is no truth to the oft-heard comment that buprenorphine is only 'replacing one drug with another'. Opiate addiction consists of the obsession for opiates; the addict's mind is taken over by the singular concern for finding the next dose. Buprenorphine effectively treats addiction by eliminating the obsession far beyond what occurs with taking an opiate agonist.

More and more addictionologists are recognizing that buprenorphine and Suboxone should be considered long term treatments.
I am sick and tired of chasing after 'contins, so I'm going to find a doc certified to treat me with Suboxone.
by SuboxDoc November 27, 2008
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The suboxone can only be properly dosed if you are smack dab in the middle of your withdrawal, so the doctors can see the level of dependence. They say stop taking everything 48-72 hours before your appointment. You should be dosed right there in the office that day. I have had many friends with success but some had relapses too because if you stop your suboxone therapy too soon the craving returns as intense as before the treatment. We all have our struggles and demons. If you're reading this considering suboxone therapy, please know you're not alone. I start in two weeks. I'm scared, but I'm ready.
I am spending way too much money on these pills, but I can't stop by myself. Maybe I'll try suboxone therapy.
by ellam71106 May 12, 2009
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An orange tablet containing Buprenorphine and Naloxone in a 4:1 ratio, used for detox or maintenance treatment of opiate addiction (to heroin or other narcotic painkillers). Methadone is used for the same purposes. Pills come in 2 and 8 mg dosages. Subutex is similar to Suboxone, but has only Buprenorphine and no Naloxone. The Naloxone is an opiate antagonist, and is put in Suboxone in order to prevent the tablets from being injected. Naloxone is not active when the pill is used sublingually, orally, or insufflated. Not commonly used recreationally, because it won't get someone with any tolerance high like Vicodin, Oxy, or Heroin would. It is valued on the street by some opiate addicts who want to have something to keep them from withdrawing if their dope supply runs short.

If you take Suboxone too soon after an opiate, you will go into withdrawal. If you take an opiate too soon after Bupe, the bupe will block the effects and you won't get high.

"I've been banging H on a daily basis for 6 months, but I think it's time to throw in the towel, and get prescribed Suboxone"
by WSB15 February 21, 2006
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Suboxone is a medication that was approved in 2000 to treat opioid/heroin dependence. It contains the medication Buprenorphine which is a medication that blocks other opiates from reaching the receptors in your brain (basically saying that if you take a Suboxone you can not get "high" from heroin or any other opiates). Suboxone also contains a medication containing Naloxone. Naloxone is used to reverse overdoses of opiates. Naloxone does not interfere with buprenorphine's effects when Suboxone is taken sublingually (dissolving under your tounge) as prescribed. The naloxone is there to deter people from dissolving Suboxone and injecting it, b/c the naloxone can cause severe withdrawal symptoms very rapidly. Suboxone comes in 8mg & 2mg strengths. They are stop sign shaped and are orange and taste like lemon-lime. There is also Subutex which is only buprenorphine, w/o naloxone and these may be used to start people on treatment for opioid dependency.
by chloe84 February 05, 2010
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I currently take suboxone and i will tell you the real deal about them. As stated above, yes suboxone is buprenorphine and naltrex (or Narcan)in a 4:1 ratio. Our brains have 3 different receptors that accept opiates, delta kappa & mu. Mu seems to be the receptor that causes the body to become dependant on different opiate substancs. Since suboxone is a "partial-opiate" it only acts on delta and kappa receptors, thus relieving the users withdraw symptoms. The Naltrex(or Narcan) which blocks opiates from binding to receptors, stops them from working. Naltrex(narcan) has a half-life of 2-3 hours... which means it is active in your body for 6 hours, 8 hours just to be safe. Since i take suboxone daily i know you can take an opiate the same day. For example: I wake up at 10am take my suboxone and by 8pm that night I can take an oxy and not go through any withdraw. In reguards to this drug not having a market on the street and the do not crush warning above, that is all BS. I have lived in 3 major citys and have found markets for suboxone in all of them. Also, if you crush up a suboxone and snort it, it will be stronger than taking it sublinguily and you will not withdraw that is a myth, believe me i have done it. I do not inject anything so i will not address that issue. Party safely please people.
"Let me cop a subby" = Let me buy a suboxone
"Got and stop signs" = Do you have any suboxone?
by Pstardirtyfrank November 27, 2006
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