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A Hanna-Barbera canine cartoon saying for "Uh-oh," beginning with THE JETSONS' Astro (1962) and continuing with Scooby-Doo in the Seventies.

Astro tended to speak a kind of English except that words with beginning consonants were replaced with an "R," and "R" was inserted in front of vowels.

Scooby-Doo was less fluent, but was given "Ruh-roh" as a kind of running gag when things were going bad.

Now "Ruh-roh" is sometimes used as a jocular trope where dogs are concerned, as in a recent news story about a dog who was accidentally released by Air Canada from his cage at the San Francisco airport. Rough meaning: "I goofed" or "I'm in trouble."
"Astro, if you don't stop that you're going to be in big trouble."

"Ruh-roh."

"Alright Astro, you asked for it, no outdoor privileges all weekend."

"Raw, Rorge!"
Ruh-roh by al-in-chgo October 11, 2013
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Guy 1: OH SHIT MY HOUSE BURNED DOWN!
Guy 2: RUH ROH!ahhahaha
ruh roh by remright September 6, 2003
Related Words
rohan rohit rohith Roh Rohin Rohullah Rohail Rohilla Rohini rohto
Jai-roh is a compound adjective as well as a noun. If anything it is a description of a way of life. It personifies lad culture into a mere two syllables that can be used to charm or manipulate disgraced chikas.
one lad: heard you got a piece last night?
other lad: yeah i was elbow deep in a mad chika, she wouldn't leave the next morning so I had to pour ice cold water on her.
one lad: thats so Jai-Roh
Jai-Roh by jai-roh judge October 18, 2011
Scooby Doo's comedic mispronunciation of "Uh Oh", it is also a play on potentially dire situations, usually starting with a minor event that could escalate into something huge.
North Korea just shelled a South Korean island? Ruh Roh!

There is a small leak from the dam? Ruh Roh!
ruh roh by sanjuro_kurosawa November 26, 2010

Ruh Roh Raggy 

A common phrase used by Scooby Doo or many others, often to show fear or intense emotions.
Ruh Roh Raggy Fred is jacking off to among us again!

Fos Roh Dah 

When the force of your load blows your girlfriend over a railing in which you were having sex.
Dude, I used a Fos Roh Dah on my girl last night. She loved it.
Fos Roh Dah by KrashMan July 9, 2012
expression used in place of "uh oh"
derived from the popular cartoon show, Scooby Doo
Kelly: "That girl hooked up with Shaniqua's boyfriend, she's gonna get the shit kicked out of her during lunch today."

Amanda: "RUH-ROH."
ruh-roh by chiquitaLOCAA January 3, 2009