When searching through your head for a comeback for your worst enemy, use this mix. Sko is a word used to describe someone who is both a skank and a hoe.
That girl over there tried to sleep with my boyfriend...she is such a sko!
by Stashizzle September 22, 2009
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cross between a slut and a ho
Lauren: "omg Grace, did you see that Sko?"
Grace : "wtf! yess."
by Cool little person January 15, 2010
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Guy 1: Hey Sko Bro!
Guy 2: how did You know?
Guy 1: we still talk sometimes.
by Anonymous9876543210-1 May 22, 2013
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Name refers to either one of two large apartment complexes in the suburbs town of Skokie, Illinois. Both buildings are located near Church Street between Keating and Lavergne Avenues. The name might also refer to parts of the town considered to be "ghetto" by wealthier residents. Just like its namesake, the O Block residential apartments in the neighboring city of Chicago, the name "Sko Block" may also be written as Sko'Block or Sko-Block.
Person 1: Aye boy you tryna slide to Sko Block today
Person 2: Oh hell naw dog I ain't tryna get popped
by tookhertothesko October 27, 2022
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Once said by Shanda Knipe.
"Skank" and "Ho" put together.
by Dannie Sherrick April 22, 2005
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skanky ho. was invented in Lancaster, UK.
"god, Bethan, you're such a sko!"
by KillMeCynic March 5, 2005
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An altered and faster way of saying Lets go. Frequently used after a sign of dominance or winning.

Pronounced: Skeh Sk-oh
Chad:"Just got an ace on Rainbow Six: Siege! Ske-Sko!"
Gabriel:"Ske-Sko!"
by Toto!Africa July 1, 2018
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