To eradicate a whole group of people. From Star Wars III: Revenge of the Sith when Darth Sidious ordered the genocide of all Jedi in order to ensure the Sith's possesion of the Republic.
"Damn our team just got Order 66'ed"
"He just got order 66'ed"
---
Darth Sidious: Execute order sixty-six.
Clone General: It will be done, my Lord.
by Melonzman May 23, 2005
Get the order 66 mug.
Verb

The act of or solicitation of someone (to another) to murder or cause harm to Nico123o with great force or destruction in order to win the match.
by Nico123o November 4, 2018
Get the Execute Order 66 mug.
When someone you love and (assumedly) loves you, such as a close friend you trust or even a lover, suddenly deletes/blocks you for no reason from all social media and cuts ties from you for absolutely no reason. It's the ultimate betrayal and it hurts a lot (as seen in Star Wars Episode III).
I can't see Aaron's posts on my Facebook. Oh wait, I think he blocked me. What the hell!? We were very close friends and I even began to love him *cries*

Sorry, looks he went execute order 66 on you.

*weeps even more and has suicide thoughts*
by avialae July 19, 2021
Get the Execute order 66 mug.
The act of deviously getting someone to leave without telling them to actually leave.

Based loosely from the term in Star Wars Episode III.
She was getting on everybody's nerves, but I Order 66'ed her.
by Hammerdown77 January 20, 2011
Get the Order 66'ed mug.
Without explanation, you abruptly interrupt intercourse to answer your phone and reply "It will be done my lord." Then commence to fiercely attack your partner until one or both of you is dead. Bonus points if you are in a polyamourous orgy and get others to join you.
"Annie and I were really going at it when I Order 66 'ed her - so if you could pay my bail, I'd really appreciate it."
by Robert S. Dylan, III July 9, 2023
Get the Order 66 mug.