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A misspelling of the words though or dough, that lazy idiots which never finished fourth grade use because they think it is the phonetic spelling of those words.

This is part of the de-evolution of mankind, where it somehow became "cool" to not know how to spell and some idiots believe the dumber you are, the better off you will be later in life.
Tyrone: "Hooray! I passed my final with a grade of 100! Oh boy, am I glad I spent all of my evenings studying this semester! Now with my GPA of 4.0, I'm sure to get into college at Stanford! I'm going to use my knowledge and hard work to do my part to better the human race. My family will be so proud of me!!!"
Chadwick: "yo, whaddup dun! my i brauws b on fleek!!! wuz dat tesst fo reel?? me wuz thinckin it wuz praktiss! watevurr. it awl gud. eye gawt uh sweat jawb @ mikdonnuhlds sow eye downt nead 2 finnish skoool now. wat b a GPA doe??"
Tyrone: "Nevermind..... I should just jump off a bridge right now..... It's too late, there is no hope for humanity"
Chadwick: "wut iz humanity?"
Doe by BHartron November 17, 2015
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The Chinese word for "fuck"(屌) being rotated 90 degrees.

(used commonly by Cantonese and people who speak Chinglish)
DOE!!!! Who raped my dog???!!!
DOE by BernardAsshole October 24, 2011
A term commonly used in place of the word "though" to add some sense of cool to the end of a sentence.
But you weren't sayin that last night doe
doe by Jaffray July 15, 2011
1-Money.
2-An endearing term for a stupid person or dumbass.
50 Cent's IN DA CLUB: "My flow, my show, brought me the doe".
doe by Fangsta March 19, 2003
The stage of life between girlhood and womanhood. A Canadian slang term which is the female equivalent of "guy."
University guy 1- How ya doin man? Met any does recently?

University guy 2- Nah, I'm still looking.

University guy 1- That sucks! I've just started dating a doe I work with.
Doe by LazyLaD September 2, 2013
n. A gangster version for the word "dawg".
Eh yo shaw-ty, me and yo momma gon' hook up on da fifteen of Decemba, aight doe?
Tyrone kicked in the front doe of that apartment to rape the bitch inside and steal her TV.
Doe by Maxwell August 30, 2004