one-and-done

A single-dose vaccine shot -- unlike the two-dose vaccines from Pfizer-BioNTech, Moderna and Oxford-AstraZeneca.

Breaking news: “Experts on the one-and-done advantage offered by a COVID-19 vaccine”
The ease of distribution offered by a single-dose shot and its ability to be stored in a regular fridge are among the new vaccine’s biggest strengths

by humblepiece April 27, 2021

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roust one

to smoke a blunt filled with weed. preferrably georgia peach flavored wraps

Yo dude do you want to roust one later today.

by lilpimpA45 May 18, 2006

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one head

stooped

lmao u just threw ur keys in ur locked car u one head

by Sir Bebe April 26, 2021

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One Lip

When you drink an alcoholic beverage in one go.

"ONE LIP! ONE LIP!"
As everyone procedes to chug down a beer.

by Tierique August 21, 2017

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Cute One

Lindsay's perfect guy is a "Cute One". He's simply not just handsome, strong, or sexy. He has a sparkle in his eye when he speaks. A perfect smile, because it's so filled with life. He's also hilarious. And something about him hints at subtle depths. Most of these types are named David.

Goodnight Cute One!!!

by Lesbiantics November 20, 2016

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One Piece

An anime about pirates finding a treasure with episodes that seems that its never ending. You either fall in love with the anime or you absolutely hate it. No in between. IT'S THE BEST ANIME IN THE WORLD IT CAN'T COMPARE TO ANYTHING ELSE.

NPC: "Hey have you heard about that weird series One Piece?"
PC: "Oh you're talking about ONE PEAK????? IT'S NOT WEIRD YOU LONG BACKED ASSHOLE."

by manstabber November 5, 2022

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