one drink syndrome 

When you have only one drink and it makes you super tired so you have to continue drinking or else you'll fall asleep.

Smith: "What's wrong with you? You look exhausted?"

Lisa: "Ugh one drink syndrome!"

Smith: "Better start drinking more"

one drink syndrome by JsnLvr May 11, 2010

All In Syndrome

Acronym: AIS

A poker analogy which applies to a one night stand that's dragged out because the girl still hasn't given it up.

The player feels they've invested too much to back out now.

John: What's Doug still doing with that girl? It's been 2 months and he still hasn't sealed the deal.

Mike: He's got classic All in Syndrome, he's spent weeks as her 'boyfriend' and has yet to reap any benefits.

John: That's weak, he needs to man up and cut his losses.

Mike: Agreed.

All In Syndrome by LongfeatherTheGreat July 8, 2010

Last Cup Syndrome (LCS) 

When you are struggling to hit that last cup in beer pong

Alright, time to get over last cup syndrome (LCS) and end the game.

Last Cup Syndrome (LCS) by pizzo91 September 18, 2010

Wandering Old Man Syndrome 

A state in which one finds themselves randomly walking around, usually without a set course or destination.

Man 1-"What's he doing? That's the third time he's walked by the doorway."

Man 2-"Dunno, must have Wandering Old Man Syndrome."

Wandering Old Man Syndrome by Khozo September 23, 2010

The Peter Stone Syndrome

To have some form of romantic relation with someone one day, and the next day that someone chooses to ignore you for a long period of time. You, the victim, feel the need to confront that someone, but when you do so, you get shot down and then you die.

"'I think I have The Peter Stone Syndrome...' 'You mean your life completely sucks right now?' 'Yeah basically I'ma jump too high on a trampoline and get rocketed into space and die now.'" Beware of The Peter Stone Syndrome. BEWARE!

The Peter Stone Syndrome by Crystal Boust November 19, 2010

Pre man-strual syndrome 

When a man has symptoms similar to when a woman PMSes.

Like, getting mad/annoyed at simple things and taking it out on you.

John: YOU LEFT THE FUCKING MILK OUT!!! WHAT THE FUCK??? I MEAN I WORK SO HARD *Cries*

Meagan: Uh... What's up with John?

Steve: He's got pre man-strual syndrome.

Pre man-strual syndrome by CapnNorris December 25, 2010

Online Degeneration Syndrome 

The increasing tendency for the online community to embrace the degenerative tendencies of human anti-socialization.

Example of online degeneration syndrome:
My definition of kitten telekinesis got reject in under 2 hours, however my definition outlining an angsty rant about internet voyeur inorgasmia was published in the same 2 hours.

Online Degeneration Syndrome by p@$$ing thr.ugh January 1, 2011