Horny cell layer

The stratum corneum (Latin for 'horny layer') is the outermost layer of the epidermis. The human stratum corneum comprises several levels of flattened corneocytes that are divided into two layers: the stratum disjunctum and stratum compactum. The stratum disjunctum is the uppermost and loosest layer of skin. The stratum compactum is the comparatively deeper, more compacted and more cohesive part of the stratum corneum. The corneocytes of the stratum disjunctum are larger, more rigid and more hydrophobic than that of the stratum compactum.

The stratum corneum is the dead tissue that performs protective and adaptive physiological functions including mechanical shear, impact resistance, water flux and hydration regulation, microbial proliferation and invasion regulation, initiation of inflammation through cytokine activation and dendritic cell activity, and selective permeability to exclude toxins, irritants, and allergens. This layer is composed of 15–20 layers of flattened cells with no nuclei and cell organelles. Their cytoplasm shows filamentous keratin. These corneocytes are embedded in a lipid matrix composed of ceramides, cholesterol, and fatty acids.

Oh look, it is the horny cell layer

by epicthing July 29, 2021

a hole in the brozone layer

When a large group of bros are talking in a strictly-guy conversation, and a girl tries to jump in and contribute

Jessica caused a hole in the brozone layer when she tried to join into a conversation about last night's party that the jocks were having

by Jakers October 20, 2015

pipe layer

The guy in your office that craps himself to death three or four times per day.

I herr dey be settin' up a computer in the bathroom for that pipe layer two cubicles over, cuz he's always in there doin some kind of work.

by tim-tim April 23, 2004

Monkey Layer

A woman that has intercourse with a black person.

That fucking whore is a monkey layer!

by Dav1d Ownz U August 13, 2005

Layer Cake

When you shit and you think you're done so you go and wipe only to find out you still have to shit more. So you wipe again and that first wipe becomes the first layer in your bathroom layer cake.

Do you ever take a dump and it's one of those layer cakes? That's what I'm experiencing right now.

by FrequentShitter February 15, 2017

7 layers

A really fat woman's stomach

I can't believe you slept with that woman. She was a total 7 layers.

by Randolph Swanson September 25, 2003

Brozone Layer

A place worse than the friend zone. The brozone layer occurs when the girl you like deems you a "brother to her." There is almost no chance of getting out of the brozone layer.

See Friend Zone

Bro 1: hey man hows it going with that chick
Bro 2: she put me in the brozone layer :(
Bro 1: You're fucked

by igotbrozoned March 28, 2012