craniorectal disease

A disease or condition of having one's head lodged up their ass. See dubya

The prez has an uncurable case of craniorectal disease.

by headinass November 29, 2003

Penialfungial Disease

Causes the penis to become engorged with fluid, thus making it much larger, then it falls off.

Dude, Jimmy had Penialfungial Disease, poor guy.

by Timmy and the Hosebags March 2, 2009

Prestige Disease

A disease which causes many teen males to stay home from school in order to rank up on call of duty. The only symptoms of prestige disease are a long period of time spent playing the game, and rapid ranking up by a player on Xbox.

"Mike, do you know why Paul never showed up today?"
"I heard he stayed home because he has prestige disease, he has played two days of Call of Duty in the past week."

by TheGreatJamal April 8, 2010

noassatall disease

A condition in which you have "No Ass At All".

Do YOU suffer from Noassatall Disease?

by BingeTrigger September 3, 2016

Fotovat's Disease

Horrifying gastrointesinal distress. Also referred to as the Colonocalypse.

"The unsuspecting tourist ingested some bad water and was stricken with a severe case of Fotovat's disease."

by Hwhite Bol December 27, 2009

will hall disease

Someone who has AIDS, Stage four testicular cancer, down symdrome and autism all at the same time

WTF’s wrong with you! Do u have Will Hall Disease

by Yeetimus Maximus July 6, 2018

Anime Protagonist Disease

When an Anime Protagonist is born, 1 or both of their parents are going to die very soon from "Anime Protagonist Disease".

Anime Protagonist: *is born with blue hair
Doctor: i'm sorry to say this, but you now have Anime Protagonist Disease
Mother: Do i have to die or him?
Father: why not BOTH?!

by Dancchi February 10, 2021