To adapt a new lifestyle which is in stark contrast to the one you previously had. Generally used when someone who previously followed rules and regulations begins to deviate from them to achieve new goals/desires. The term is most often used when someone who is generally accepted as "good" adapts behaviors which are seen as "bad".
"What he's just gonna break bad?” Jesse Season 1, Episode 1 Breaking Bad
"Walt broke bad when he was diagnosed with cancer...."
To smoke enough DMT for a very immersive and intense trip, usually lasts around 15 minutes and in which almost all connection to the real world is lost. Many who have broken through describe it as a life changing experience, but other than that the trip is indescribable.
Yo man I got some DMT u wannabreak through tonight?
Nah man I did last night, that was some freaky shit.