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In Greek Mythology she was a woman caught banging Poseidon of the altar of Athena. Athena got really pissed and made Medusa really ugly, with snakes for hair.
Medusa is one person that you don't wish to anger.
Medusa by Pagan chick June 7, 2005
A piercing on the center of the upper lip, below the septum.
Medusas, are in fact, very painful. They are not very common, but can still be found adorned on the bodies of body modification culture.
She pierced her Medusa while at the Body Art Expo.
Medusa by myspace.com/4509496 August 27, 2007
That one girl who if you look into her eyes even once, you'll start to fall for her. Lighter colored skin makes it worse, as it'll bring out the eyes more, making it more likely for you to fall.
Damien: Woah, who is she?
Jerry: Darlene? Don't get into her, she's modern day medusa. One look and you're hooked.
Medusa by Snake Forgot September 19, 2016
A gangsta from the Mediterraneran or with Mediterranean origins - Italians, Spaniards, Greeks etc. Usually implying mafia and organised crime.
'The Medusas are exorting my shop'
'Wtf are those fukin medusas doing outside my house.
Medusa by Mark Doust September 4, 2005
a woman who who is so ugly that when you look a her you turn to stone
Last night after my beer goggles wore off, i looked at the medusa next to me and i turned to stone. HOLLER!
medusa by GGGGGGG-UNNNNIITTTT September 20, 2003
A strikingly beautiful female. Means the opposite of "Medusa" (the mysthological character).
No one tan touch her looks, she's a medusa.
medusa by Jim December 3, 2004