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Irritable Jowel Syndrome

A chronic disease suffered by a good friend of mine. Symptoms include yakking it up when he should be keeping his pie-hole shut.
Ken:Hey Norm, remember the time you, me & the 3 Mormon chicks....
Norm: Hey Ken, STFU! My wife's right here and doesn't need to hear about how I banged that Morman every day for 2 straight months in a row! You f*ing have irritable jowel syndrome, dude~~
Irritable Jowel Syndrome by Bangboy December 26, 2009

run the jewels 

To rob someone.

Also a dope hip-hop group.
"Yo dawg, I'm about to run the jewels on this broad walking by"
"Nah son, you don't want to do that, you'll get locked up for years"

"The new album by Run the Jewels is amazing. Killer Mike and El-P at it again."
run the jewels by lastblockbuster November 2, 2014

Family Jewels

Family Jewels is slang for a man's penis and testicles, which are important for having a family and also for sex. The sperm is stored in the testicles! Also, getting kicked in the family jewels hurts a lot!
Bully: Eat dirt!

Bobby: That's my purse! I don't know you! *kicks Bully in the Family Jewels.
Bully: Ahhhh!*Collapses to the floor.
Family Jewels by HawaiianPunch1 April 13, 2023

johnson family jewels 

the sack of stones attached to a johnson, the balls on a dick
"ouch, that soccer guy just took one in the johnson family jewels."

--also, every episode of america's funniest videos includes at least one guy getting whacked in the johnson family jewels by a kid with a baseball bat, golf club, a kid swinging at a pinata, or some other predictable manner

drop jewels 

Midas dropped some jewels on me on how to treat my girl.
drop jewels by Jolene February 14, 2005

run them jewels 

An expression used when robbing someone to denote the desire that he or she relinquish the jewelry that he or she posses.
Run them jewels nigga! Give me them watches, them rings, and bitch...Give me that motherfuckin' necklace!