To COMPLETELY dominate somthing or someone
I totally guffed you up
by DFG January 14, 2003
Get the guffed mug.
to be completly off your face on weed

comes from south affrica
u look competly guffed
by wierd is a good thing February 10, 2005
Get the guffed mug.
When another does an audible guff (fart) and you decide to drop a silent one on the back of theirs and blame them for the offensive odour
Mark: "parrrrrp" Whoops, sorry, couldn't hold it in any longer
Baz: "Pfffst" ... OMG Mark, that smells gross, you got dead rats up your bum
Mark: You sure you're not Piggy Back Guffing again as mine don't smell that bad
by Fatcatkim November 3, 2011
Get the Piggy Back Guffing mug.
A physical interaction from someone, or something, that is intended to platonic, though in rare cases can be romantic
"Man, Sasha just gave me a guf!"
by ANC13NT_R1C3 May 8, 2022
Get the Guf mug.
Going until failure. Hitting as many reps as possible while lifting weights
I’m about to GUF on bench right now!
by Ad25 February 14, 2019
Get the Guf mug.
Verb: Guffed
1. Stands for

Gay
Ugly
Fat
2. A person that eats sand and shoves it up their nose
3. Someone that eat shit out in their backyard
E.g.

1. Ew get away from me you guf person
2. Go back to the desert you guf
by By Ella the amazing biotch 😻 November 29, 2021
Get the Guf mug.