WIS 

WIS (Wisdom) is a stat in D&D and other role-playing systems.
From D&D wiki:
"Wisdom describes a character’s willpower, common sense, perception, and intuition. While Intelligence represents one’s ability to analyze information, Wisdom represents being in tune with and aware of one’s surroundings."

All the Gamer fanfics with characters whose WIS is too low to realize they desperately need to allocate more points to WIS are a horrible allegory for this reality.

WIS by papayathreesome April 14, 2021

Wis 

An inside joke that no one on Urban dictionary wil understand

Stop wis-ing around Lee

Wis by Lee-kun August 19, 2021

wis 

It’s basically short for sister or sis but in a cuter way, swis but in a better way. You can also say wissy!

“I love you wis/wissy!”

“Goodnight wis/wissy!”

wis by Shanhi October 19, 2021

wis 

something that fish smoke, another name for sea weed

spongebob: hey patrick wanna smoke some wis?

patrick: ok spongebob let's do it!

mr krabs: OY SPONGEBOB LET'S SMOKE SOME WIS ARRGIGIGIGIGIGIG

wis by Wissy Pissy April 28, 2023

WIS 

Woman in STEM
(acronym)

Pronounced like "miss" or "piss" but replace the m or p with a w.

"Is Maria a WIS?" Casey asked.
"Maria is such a WIS!" Paris answered.

WIS by The Nice Lunch Lady March 2, 2024

WiS 

"worst in slot"

not to be confused with its opposite "best in slot" (BiS) which is much more commonly used

logan: yo should i take sundered sky on gragas
john: i think that might actually just be wis

WiS by fishyfilth April 9, 2024

wis 

used interchangeably official meaning is pretty face but it implies something dirty and u can use it anywhere in a sentence like “sigma” or “skibidi”

Rex: “dude i my wis is huge”

Heath: “your wis is so big”

Everyone else in the class: {laughs}

wis by cqtx May 1, 2024