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Jesus Fucking Christ on a Bicycle 

"Jesus fucking Christ on a bicycle! Slow down, but don't stop." Mr. Wednesday in Neil Gaiman's American Gods, Part 2, Chapter 12.

Jesus Fucking Christ Hole 

A verbal expression of overwhelming fear when a person is startled, surprised, shocked, or scared followed by extreme anger.
While Jimmy is driving on the expressway, he is suddenly cut off by another vehicle traveling ten miles per hour under the speed limit. Jimmy: "Jesus Fucking Christ Hole! You cut me off! get the fuck out of the way!"

Holy shit, Jesus fucking Christ! What the fuck!?! 

A response to someone who is/was doing an action that is morally wrong, such as murder.
Holy shit, Jesus fucking Christ! What the fuck!?! You just killed the man!

jesus titty fucking christ

Interjection. A stronger variation of jesus fucking christ. Used to express surprise or shock.

jesus goddamn fucking christ 

1. an exclamation one would express when frustrated

2. so angry in fact you have no other way to describe it other than yelling this phrase as loud as possible.
wife: "the dishes are dirty, the trash hasn't been taken out, the dogs need to go out, pick up your clothes."

husband: "JESUS GODDAMN FUCKING CHRIST!"