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I’ve farted and I can’t get up! 

When a person is so old and so powerfully flatulent that it knocks them on their ass and they can’t get up.
This is a most pathetic scenario, I’ve farted and I can’t get up!

I've had it with these motherfucking snakes on this motherfucking plane!

Something you might shout out when you're fed up with a frustrating situation.
After dealing with aggravating bureaucrats for hours, Joe suddenly shouted "I've had it with these motherfucking snakes on this motherfucking plane!"

From the movie "Snakes on a Plane"

I've made a huge mistake.

1. An understatement to utter under your breath when you botch everything.

2. Something to say when you realize your preconceptions of the situations have turned up false.

3. Something Gob might say on "Arrested Development."

I've fallen and I can't get up 

A really annoying catchphrase from the late 80's/early 90's that originated from a commercial for a paramedical emergency radio for the elderly. During the commercial, and old lady falls off her walker and in the most pathetic tone of voice possible, utters this phrase into the advertised device.
Before everyone and their mom was screaming "I'm Rick James, bitch" they were screaming "I've fallen and I can't get up" in a sad attempt to be funny and witty.

"I've had it with these motherfucking snakes on this motherfucking plane!" 

A phrase one hollers when one is sick and tired of a situation. From the film, "Snakes on a Plane"
After hours of dealing with bureaucrats, John suddenly shouted "I've had it with these motherfucking snakes on this motherfucking plane!"

I've had it up to here 

usually used to describe when one has lost all patience for a situation or person.

an exaggerated hand movement is commonly used alongside this expression; the person raises their hand above their head flat and parallel to the ground to show where "up to here" is.
Jim: Hey, Tom. How's life going?
Tom: I've had it up to here! *raises hand*
I've had it up to here by momochki February 9, 2018