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An OxyContin 80 mg pill, whereas a Little Dog is a 40 mg pill.
I need a Big dog, or a Great Dane, how much is a pure bred? or for a little dog, I need a Schnauzer, are there any around?
Big Dog by Simmons62 January 1, 2006
One man who think he's better than everyone else, continously gets ripped on by his homedogs, usually found wearing no shirt
Wow he's driving with no shirt on, he must be a big dog.
Big Dog by 420 SHNAYZE May 19, 2010
To be a big dog is to embody what it means to be self-oblivious, to be unaware of the fact that you're the biggest meme of all time. A big dog can also be used at the tail end of an insult to boost it's credibility. Or, big dog can mean you're cool
That's a nice Overbite, Big dog.

Come to Indy, Big dog.
"Hey Tina don't worry so much! One day you'll find you're big dog!"
"Ha Bob's so awful, he'll never find his big dog"
Big dog by Looking for big dog March 10, 2015
A man dressed in a dog costume for the enjoyment of little kids. Made popular in the Newcastle region of Australia.
Did you watch Big Dog this week
Big Dog by Steve McQueen August 28, 2019
v. To kick James's ass in fantasy football.
I am big dogging James like the little bitch that he is.
Big Dog by Iced Gringo November 14, 2016