The baddest motherfucker in any group of Gs or Hustlas. The Big Dog is the shot caller and will whoop the ass of anyone present who does not fall in line.
Listen up y'all, I'm the Big Dog here, so we're gonna do this like I say. Anybody got a problem with that, then I'll knock your ass out.
by K. Washington July 25, 2016
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A term used to describe a friend, colleague, or person. Can be used in the place of Words such as Man, Bro, Dude, etc.
Come on, Big Dog.
When are we gonna go to another Red's Game, Big Dog?
by xx QuikShoT March 03, 2010
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A term bloggers use to refer to President Bill Clinton.
"Big Dog still has mucho mojo in political circles."
by Genaro Lopez January 17, 2004
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An OxyContin 80 mg pill, whereas a Little Dog is a 40 mg pill.
I need a Big dog, or a Great Dane, how much is a pure bred? or for a little dog, I need a Schnauzer, are there any around?
by Simmons62 December 31, 2005
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To be a big dog is to embody what it means to be self-oblivious, to be unaware of the fact that you're the biggest meme of all time. A big dog can also be used at the tail end of an insult to boost it's credibility. Or, big dog can mean you're cool
That's a nice Overbite, Big dog.

Come to Indy, Big dog.
by SheCleansHisOverbite May 21, 2018
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One man who think he's better than everyone else, continously gets ripped on by his homedogs, usually found wearing no shirt
Wow he's driving with no shirt on, he must be a big dog.
by 420 SHNAYZE May 18, 2010
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