yolo 

San Francisco Bay Area slang for cocaine

I don't buy yolo because I don't want to bankroll the CIA

yolo by rezrez June 13, 2007

yolo 

You
Only
Live
Once

You only live once that's the motto nigga YOLO!!

yolo by Bison! March 14, 2012

YOLO 

Technically the more badass version of this is the song by Suicide Silence's signature song, You Only Live Once... Or if you're a preteen girl then there's that...

Gonna swear at my teacher. Shit's bout to go down. #YOLO lol

You Only Live Once, so just go fucking nuts!

YOLO by sempiternal9 February 3, 2015

YOLO 

Like ILY, it has taken something meaningful and killed the complete shit out of it.

Hey baby, ILY because YOLO.

Hey baby, I love you because you only live once

YOLO by essjay July 21, 2012

YOLO 

Your Opinion Lacks Originality

A term used condescendingly in reply of someone saying YOLO

Tool: Tonight is going to be crazy...YOLO
Normal Human: I can't wait...YOLO

YOLO by Brayson October 2, 2012

YOLO 

(You Only Live Once) it was an ok saying at first but teenage girls ruined it for everyone. forever. whenever you here a person say it you usually get the sudden urge to smack them, or even in extreme cases Buzz LightYear them

girl: "OMG YOLO"
boy: "SHUT UP!!!" (smack)

YOLO by Doc. ChuCho October 26, 2012

yolo 

an excuse to have sex with any guy you see

Girl 1: Should I hit up Dave for a booty call? I don't wanna seem like a slut.
Girl 2: Yolo.

yolo by dude121212 December 12, 2012