Lil' Wayne Syndrome 

People who are just shit but for some ungodly reason unknown to man think that they are THE shit.

Yao Ming Jr.: I am such a fuckin pro at basketball. None of these cats can fuck wid my 6 foot 7 foot dunks. U mad?

Me: ... You bricked your last 4 dunks and you cant even make a free throw.. Are you fuckin dumb or have you just not woken up from whatever dream you were having?

Other Guy: Leave him bro, he's suffering from lil' wayne syndrome.

Lil' Wayne Syndrome by Your Mom's BOB April 9, 2012

Nigga-Head Ass syndrome 

When a black human (Nigga) has a head that looks similar to the gluteus maximus muscle. This can be used on white or black people only. The syndrome is very common.

You have the biggest Nigga-Head Ass.
Fix your Nigga-Head Ass immediately it is too big.
Blue face you have Nigga-Head Ass syndrome.

Nigga-Head Ass syndrome by Henry HandNigga April 9, 2019

The Dr. Seuss Syndrome 

The neurological condition where an individual feels compelled to turn everyday words into a rhyme, which does not change the actual meaning of the original word.

Normal Person: "That is neato"
The Dr. Seuss Syndrome: "That is neato dorito"

Normal Person: "Awesome!"
The Dr. Seuss Syndrome: "Awesome Possum!"

Normal Person: "Whatever"
The Dr. Seuss Syndrome: "Whatever Trevor"

The Dr. Seuss Syndrome by JoTySmith November 16, 2010

girl interrupted syndrome

A person (typically female) who is a self-acclaimed intellectual and philosophy freak. Nevertheless, she is an effortless cool girl, quiet, mysterious, and alluring. She may seem like the perfect girl at first glance, shockingly beautiful and incredibly different, however, she will leave you broken-hearted In the end. Those who suffer from this syndrome usually partake in distinct activities such as, cigarette smoking, listening to grunge music, reading 18th-century pretentious novels, and drinking plenty of vodka.

At the core of the syndrome is mental illness. Girls who have this syndrome are beautiful and alluring but cold and arrogant.

Max: She's just so alluring and different. I asked her what she was listening to on her headphones while she smoked her cig and she said The Smiths.
Joey: Uh oh erm... she sounds like she has girl interrupted syndrome.

girl interrupted syndrome by nymphpop September 30, 2021

Christmas Syndrome 

When you are looking forward to something constantly, to the point of obsession, causing the actual event to seem short and dull in comparison.

Oh, he's been counting down the days since July, and has came down with a bad case of Christmas Syndrome.

Christmas Syndrome by AiRsTrIkE March 18, 2011

Supervisor Syndrome 

A term used to describe a non-supervisory worker who ejoys assuming the role of a supervisor over others.

Sam has the bad case of supervisor syndrome today.

Supervisor Syndrome by Ortet September 9, 2006

Jaden Smith Syndrome 

When someone looks concerned at all times.

girl 1: "Why does Jessica look so worried all the time?"

girl 2: "She's not worried, she just has Jaden Smith Syndrome."

girl 1: "Oh. What a bitch."

Jaden Smith Syndrome by tastytacofridaysinmyass May 28, 2014