People with Trans Derangement Syndrome have been trained to have an extreme adverse Pavlovian response to anything suggesting 'trans'.
The mere utterance of the word trans or they/them bypasses the higher-thinking circuitry of the brain and triggers the primitive rage centres to go off.
The mere utterance of the word trans or they/them bypasses the higher-thinking circuitry of the brain and triggers the primitive rage centres to go off.
Person 1: “is JK Rowling ok? They seem mentally unwell”
Person 2: “no, seems like they have a serious case of trans derangement syndrome (TDS)”
Person 2: “no, seems like they have a serious case of trans derangement syndrome (TDS)”
by Robert_G_ September 4, 2025

Nintendo Derangement Syndrome (NDS) is a term to describe a condition where individuals lose all sense of objectivity and rationality when discussing Nintendo specifically those who obsessively hate the company. This often leads to exaggeration, misinformation, double standards, and bizarre emotional reactions whenever Nintendo is even mentioned. It's much more prevalent ever since the Switch 2 Launch.
You're allowed to dislike & criticize Nintendo. NDS kicks in when that dislike tums into obsession. misinformation, or irrational rage especially when you start acting like people enjoying a game is a personal attack on you.
Symptoms of Nintendo Derangement Syndrome:
• Compulsive Lying about Nintendo sales, hardware specs, or game quality
• Goalpost Shifting when proven wrong
• Downplaying Critical or Commercial Success
• Calling Fans Cultists while foaming at the mouth about a 40-second Nintendo Direct trailer
• Using Piracy or Emulation as a Moral Crusade
You're allowed to dislike & criticize Nintendo. NDS kicks in when that dislike tums into obsession. misinformation, or irrational rage especially when you start acting like people enjoying a game is a personal attack on you.
Symptoms of Nintendo Derangement Syndrome:
• Compulsive Lying about Nintendo sales, hardware specs, or game quality
• Goalpost Shifting when proven wrong
• Downplaying Critical or Commercial Success
• Calling Fans Cultists while foaming at the mouth about a 40-second Nintendo Direct trailer
• Using Piracy or Emulation as a Moral Crusade
FritangaPlays clearly has Nintendo Derangement Syndrome if he dedicated 3 months of uploads to shit on Nintendo and the Switch 2.
by LPBvgc July 18, 2025

An irrational attachment to Elon Musk, believing that the South African trust fund baby is some kind of super-genius, a sort of real-life Tony Stark, even though he didn't invent any element of SpaceX's rockets - he merely bought the company - nor did he invent any part of Tesla Motors' electric cars - he merely bought the company - nor did he create x.com - he merely bought Twitter, the most successful and popular site online, and turned it into a foul pit of bigotry.
Now that Elon is destroying one Federal agency after another with authority handed to him by donald trump, he is being credited with "ending waste" and thereby "saving billions", when he has merely shut down important functions of one of the world's great powers and cut their operations out of the Federal budget - and usually only reducing Federal outlays by a few million.
Now that Elon is destroying one Federal agency after another with authority handed to him by donald trump, he is being credited with "ending waste" and thereby "saving billions", when he has merely shut down important functions of one of the world's great powers and cut their operations out of the Federal budget - and usually only reducing Federal outlays by a few million.
"Jimmy thinks Elon is some kind of 'Great Man' because he 'restored free speech' on x.com. My x account was deleted for referring to MYSELF as 'cis'. Some haven of free speech! Jimmy is totally suffering from Elon Derangement Syndrome."
by Arcadia Jane Berger March 14, 2025

Andkon Derangement Syndrome (ADS) is a serious mental health disorder that impairs and damages the Limbic system of the brain causing intense effects such as seething, malding, balding, schizophrenia, obsession and paranoia often shown as hatred towards the prolific individual called Andkon's Reich and his ideals.
Those who suffer from Andkon Derangement Syndrome may say things like:
"Andkon's a Jew, Mulatto, Nonwhite"
or any other derogatory conspiracy theory directed or implied towards Andkon's Reich
"Andkon's a Jew, Mulatto, Nonwhite"
or any other derogatory conspiracy theory directed or implied towards Andkon's Reich
by AZog Battalion December 24, 2022

A mental dysfunction causing those detractors with schizophrenic fears and/or hateful thoughts and feelings about Johnson McGee to go unhinged. Abbreviated as MDS.
Herbert has been talking about Johnson McGee all day! I feel like he might be suffering from McGee Derangement Syndrome.
by Johnson McGee The Third April 12, 2021

An effect where people think that a country, state, province, city, or any other sort of area are far better / worse than they actually are.
Jimmy : Hey guys this part of our city is such a nice place!
John : No it isn't...
Jimmy : YEAH IT IS
John : But people get constantly robbed, shot and raped over there...
Jimmy : THATS A FALSE STATISTIC!
John : Calm it down with your Area Derangement Syndrome
John : No it isn't...
Jimmy : YEAH IT IS
John : But people get constantly robbed, shot and raped over there...
Jimmy : THATS A FALSE STATISTIC!
John : Calm it down with your Area Derangement Syndrome
by SRPGShadow June 13, 2018

Deranged Grindr Syndrome (or DGS) is a psychiatric condition affecting an unknown number of gay men who use Grindr for sexual purposes. People with DGS may exhibit a wide variety of antisocial or psychotic symptoms including:
- Ghost-facing: Attempting to engage in chat with other users without having any pics of themselves
- Hole-bombing: Sending unsolicited images of their gaping holes to complete strangers
- Pic-collecting: Requesting images from other people when they haven’t shared any pics of themselves
- Wounded ego: Impaired ability to cope with rejection, such as demanding an explanation for why a complete stranger is not attracted to them
- Silent treatment: Engaging in extensive chat with another user and indicating an interest in meeting up for sex, and then going silent and never responding again
- Ghost-meeting (different from ghost-facing): making an actual plan with someone from the app to meet in person, exchanging location details and setting a specific time, and then ghosting the person with no warning or explanation
- Stalking: tracking another user’s online presence and bombarding them with messages each time they come online
If you or someone you love suffers from DGS, help is available. Speak to a mental health professional.
- Ghost-facing: Attempting to engage in chat with other users without having any pics of themselves
- Hole-bombing: Sending unsolicited images of their gaping holes to complete strangers
- Pic-collecting: Requesting images from other people when they haven’t shared any pics of themselves
- Wounded ego: Impaired ability to cope with rejection, such as demanding an explanation for why a complete stranger is not attracted to them
- Silent treatment: Engaging in extensive chat with another user and indicating an interest in meeting up for sex, and then going silent and never responding again
- Ghost-meeting (different from ghost-facing): making an actual plan with someone from the app to meet in person, exchanging location details and setting a specific time, and then ghosting the person with no warning or explanation
- Stalking: tracking another user’s online presence and bombarding them with messages each time they come online
If you or someone you love suffers from DGS, help is available. Speak to a mental health professional.
Deranged Grindr Syndrome is like when some rando with no face pic hole-bombs you with 15 photos of their gaping anus and then demands that you unlock your private album.
by xxxtraspecial June 2, 2024
