A condition occuring over time to chronically ill patients who have to take a lot of medication, in which the patient stops taking pills because of the stress and monotony of constant pill swallowing.
"I am so tired of taking all my HIV meds. I'm full before I ever get anything to eat."
"Hey man, don't be giving in to pill fatigue now."
"Hey man, don't be giving in to pill fatigue now."
by kitandcaboodle August 10, 2006
When a girl gets tired of fucking the same cock, even though that cock might be awesome by size, girth, cumshot.
Girl #1: I cheated on Danny.
Girl #2: Why? I thought you said he had an incredible cock...
Girl #1: It's been 3 months, I'm tired of his cock, so I did a one-niter with this guy I met on Twitter.
Girl #2: Sounds like you have cock fatigue.
Girl #1: Yeah you could call it that. I'm just afraid to tell Danny, don't want to deflate his ego. There's nothing wrong with his cock. I just need fresh new cock!
Girl #2: Why? I thought you said he had an incredible cock...
Girl #1: It's been 3 months, I'm tired of his cock, so I did a one-niter with this guy I met on Twitter.
Girl #2: Sounds like you have cock fatigue.
Girl #1: Yeah you could call it that. I'm just afraid to tell Danny, don't want to deflate his ego. There's nothing wrong with his cock. I just need fresh new cock!
by sarasplayroom.com May 06, 2010
A modern disease, characterised by weariness of reading about or suffering from other modern disease, such as Compassion Fatigue, Air Rage
by Punanimal May 05, 2006
Comparable to metal fatigue, friend fatigue is a condition contracted by an individual from a self-centered friend as a result of that friend's endlessly repeated tales of misfortune, failure, unhappiness, or success, achievement etc. Freeloaders, depressives and comedians (people who have to make everything a joke)
are character types that are often carriers of this social virus. A person who contracts FF often will usually end up avoiding the carrier. Ironically FF carriers are immune to FF.
are character types that are often carriers of this social virus. A person who contracts FF often will usually end up avoiding the carrier. Ironically FF carriers are immune to FF.
For 20 years now Caroline/George has had a series of disastrous love affairs. 5 minutes ago he/she called and already I am being subjected to the latest sad episode of misplaced trust, betrayal, and consequent anguish. I feel my head beginning to tighten and an urgent need to cut off the call. For Caroline/George I no longer feel anything, least of all sympathy. I am in an advanced state of "Friend Fatigue".
by Gilssement June 10, 2009
The feeling of anxiety and lethargy produced after several failed attempts to login on a website. This condition afflicts millions of people on a daily basis.
by soobes December 16, 2009
Pride month gave me pride fatigue.
by kalle609 June 29, 2022
After living in Portland for the past twelve years amongst their hipster friends, Bob and Simone began to suffer the onset of kitch fatigue.
by Chet Stuyvesant January 19, 2007