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(1)Complete reversal of previous positions on important or trivial matters affecting everyday life ... normally but not necessarily appearing when one turns 50+ ...

(2)Suddenly giving up on previously held beliefs ... Flipping-flopping on a given issue ...
Bob is a peace activist his entire life, but while on his death bed, he decides that conflict is a necessary action of humanity, he is obviously suffering from "Old Man Derangement Syndrome".

Fran is a life long Republican, but when she turns 60 years old, Fran becomes a Democrat, throwing away long .held political beliefs.

Jim believes in marriage being between a male and female, but in his later years of life, decides marriage can be between a male and female, a male and male, or a female and female.
by HatesOldManFlipFlopping November 9, 2012
mugGet the Old Man Derangement Syndromemug.

Heard Derangement Syndrome

"Heard Derangement Syndrome (HDS) is a mental condition in which a person has been driven effectively insane due to their dislike of Amber Heard, to the point at which they will abandon all logic and reason."
Depp fanatics are so consumed by their Heard Derangement Syndrome (HDS) that they don’t stop talking about Amber Heard.
by IStandWithAmberHeard June 21, 2022
mugGet the Heard Derangement Syndromemug.

Taylor Derangement Syndrome

Taylor Derangement Syndrome (TDS) is a mental condition in which a person has been driven effectively insane due to their dislike (or like) of Taylor Swift to the point at which they will abandon all logic and reason. (Mostly seen in grown men and women who previously had indifferent opinions on the artist)

Symptoms may include:

Heart palpations
Thinking in Taylor Swift lyrics

Craving pumpkin spice

Posting online rants
Sacrificing voodoo replica dolls of swift haters
"Did you hear about Maiko? They put her on a 72 hr lock down because of her Taylor Derangement Syndrome!"

"Why is everyone fighting about Taylor?!"

"I think they have TDS! "

"Omg I would die for Taylor. I spent my entire life savings on bleacher seats!! In my broke era!!"

"Bitch, you might have TDS"
by Maiko182022 October 8, 2023
mugGet the Taylor Derangement Syndromemug.

Chuck Todd Derangement Syndrome (CTDS)

Fully justified wave-of-fury affecting ALL "Meet the Press" viewers
Carl had seen "Meet the Press" one too many times. "why am I even allowing my DVR to tape this fucking garbage? Chuck Todd is a disgrace and obviously a mouthpiece for disgraced Qpublicans. what a fucking choad!" Carl exclaimed as he chucked his beer stein against the wall. poor Carl had Chuck Todd Derangement Syndrome (CTDS), so he decided to start a support group in his area.
by Uncle Joosie December 23, 2022
mugGet the Chuck Todd Derangement Syndrome (CTDS)mug.

GDS (Gavin Derangement Syndrome)

A mental disorder, disease that afflicts MAGA, who have negative views on the democratic party and will do unjustly things for Trump only, and claim he is superior in anyway and will never find fault even if he is a pedophile.
@NullenM: You need mental help for your GDS (Gavin Derangement Syndrome) LOL 😂

@gypsytears75: Fuck you. I live in CA he’s a piece of shit
by anonymous August 15, 2025
mugGet the GDS (Gavin Derangement Syndrome)mug.

Owen Jones Derangement Syndrome

You look the other way when your friends massacre, rape, behead, etc and speak up when people you dont like fight back against rapists, invaders, mass-murderers, etc
The Guardian columnist suffers from Owen Jones Derangement Syndrome - this explains why he downplayed Hamas 7/10 massacre whilst rallying against Israel defending herself to prevent more massacres
by anonymous November 29, 2023
mugGet the Owen Jones Derangement Syndromemug.

Grafton Derangement Syndrome

A psychological disorder that prohibits a person from using rational thought of any kind when not being able to tell the difference between right and wrong. Irrational behavior and lunacy follow shortly after first symptoms appear making that person look highly unstable.
There was a small leak in the hull of a boat fueled buy a few members of the crew with Grafton Derangement Syndrome (GDS) everyone jumped overboard and drowned instead of patching the small hole.
by 123456# July 27, 2025
mugGet the Grafton Derangement Syndromemug.

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