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ur sister a mister 

If the "Your Granny and TRANNY!" get pulled out you must say "YOUR SISTER A MISTER!!" and this rude human will die of brain cancer.
Tim"You are a cunt"
Me"No you"
Tim"Ur dad has big gay"
Me"No u"
Tim"Your granny tranny"
Me"Your sister a mister"
Tim *DIES*
ur sister a mister by Gayuun May 10, 2018

ur sister mister 

Ur sister mister is the next level of ur granny tranny. It is stronger than ur mom gay, ur dad lesbian and ur granny tranny combined. Nobody who ever heard this sentence is alive.
John: Hey Jeff ur mom gay
Jeff: No u
John: Ur dad lesbian
Jeff: Ur granny tranny
John: Ur sister mister
Jeff: *jeff and his whole family instantly die and go to the deepest layer of hell*

Ur Sister's a mister 

It is almost As worse as ur granny tranny, but instead the Sun moves close to Earth not the Earth closer to the sun
Jake: Hey Shawn what's up?
Shawn: Your sister's a mister!
Jake:......

carousel sister

When two women have had sex with the same guy.
carousel sister by Alt_Queen May 13, 2018

Ur sister a mister 

The worse possible insult above "ur mom gay" "ur dad lesbian" "ur granny a tranny" and "ur granpap a trap"
James: lol ur mom gay
Holden: ur dad lesbian
James: ur granny a tranny
Holden: ur granpap a trap
James: well ur sister a mister
Holden: *shrivels up and dies*

ur sister fister 

worse than ur mom gay and ur dad lesbian and worse than ur granny tranny combined
trevor: yo kyle ur granny tranny
kyle: ur dad lesbian

trevor: no u
kyle: ur sister fister
trevor: *dies instantly sun breaks a piece of*
ur sister fister by lolfagit 101 March 20, 2018