Dukes is an area in the video game: Grand Theft Auto 4, in which it is resembles The New York area: Queens.
by GTA Fan April 17, 2007

An ailment prevalent in the cheffing community during the summer months. Most commonly resulting from a combination of sweat, heat and friction leading to a chaffing rash between the thighs. Symptoms include walking like John Wayne.
Cook1: You're walking like you got fucked in the arse... your woman make you go horse riding again?
Cook2: Nah mate, I got the duke.
Cook2: Nah mate, I got the duke.
by achef January 11, 2012

Where one is extremely intoxicated on many illicit substances and/or solids. Phrase coined by one they call; 'Luke the Duke', who is quite frequently 'duked'.
by Crazzz January 19, 2008

by princessdiva1010 September 9, 2020

If you can't decide if someone is a dick or a douche, they can be a Duke. Often refers to competitors in business. Someone who is not well liked.
by stmshppr February 22, 2010

yo im with my dukes just now where you at?
by Mr. 6ixLawd May 29, 2019

Meaning raped. Refering to the Duke Lacrosse team scandal that happened in 2006. Originating in a small town of Maryland's Eastern Shore.
by BBP April 9, 2007
