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Not deriving from Scary Movie like everyone says, it derives from an old Budweiser commercial. It is used to say "How are you?" "What are you doing?" oor just "What's up?"
Buddy:Wazzap?!?!
Guy: Nuhin' B. Watchin' the game, havin a Bud. Sup wit'chu?
Buddy: Nuhin', watchin' the game, havin' a Bud.
Guy: True, true.
Wazzap by Giovanni Mann March 31, 2009
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i`m just going for a wazz:)
wazz by Cara May 19, 2003

wazzzup!!! 

to say hi or sup, or to be exited
wazzzup!!! by geoff March 9, 2003
A popular word in New Orleans (MURDER CAPITAL) thats short for whats up or as white kids say how you do!!!!!!!!!
Say round wazzam with you.
wazzam by Spitta November 24, 2007
1. The popular shortened word version of the video game Wizard101.
2. A game about wizards fighting together to save their world.
Josh: Hey what are you doing?
Elena: Going to go on wizzy.

Josh: You on wizzy?
Matt: Yeah, log on, I need some help.
Wizzy by maniamsmart February 17, 2014
the Budweiser slogan, where drunk people call eachother on the phone and go "WAAAAAAAAZZZZZZZZZZZZZZZZUP??" and expect no responce.
*Picks up phone and calls pothead friend* "Hey Billy, WAAAAZZZZZUUUUPPPP*
wazzup by Staycie July 5, 2003