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Oy with the poodles already! 

Taken from the popular dramedy 'Gilmore Girls' (2000 - 2007 R.I.P.) starring Lauren Graham and Alexis Bledel, this phrase can be used to shut up a person that is talking non-stop about a certain subject.
This phrase can be heard in the opening of the episode titled "I Can't Get Started" (season 2, episode 22) when Lorelai, played by Graham, mentions that "oy" and "poodle" are the two funniest words in the entire world. She says that if you put them togther in a sentence you'd have a catchphrase that's "knocking 'What you talkin' about, Willis?' right out of first place".
Girl 1: "Oh emm gee! Can you believe how Brad just absolutely left Jennifer for that big-lipped freak Angelina Jolie?! I mean, come on! They were sooooo cute together! And unless you've been living under a rock since '04, you've heard about it! I feel sooooo bad for Jenn. It was just so unfair for that poor excuse for an actress to come and steal Brad! Of course, Brad is to blame too! It's just like a man to go cheating like that. And then there's the fact that-"

Girl 2 (interrupting): "Oy with the poodles already!"
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the most commonly used phrase by female Mexicans experiencing orgasms. In English it means "oh daddy!"
Jorge: "How ya like that baby?"

Maria: "PUT IT IN DEEPER!"

*Jorge moans*

Maria: "OY PAPI MAS RAPIDO"
OY PAPI by 69in May 31, 2010
Related Words
oy Oyster (oYo) oye oy vey Oyk oyg oyasumi oyin OYA

Oy yoi yoi

A reduplicative diminutive of oy expressing frustration or exasperation.

Variant spelling: oi yoi yoi
Slipping down in his hospital bed, Grandpa Vince says upon seeing his son, "Oy yoi yoi."

Boston Legal. The Good Lawyer. Season 3, Episode 16. Teleplay by David E. Kelley.
Bethany Horowitz: "Oy yoi yoi. Just do it."

Painting by Roger Hilton at the Tate Gallery in Britain: Oi Yoi Yoi (1963)
Oy yoi yoi by Paleohippie June 11, 2008
A salutation of recognition from the UK, often shouted, sometimes in an ironic manner.
oy oy by Ian Chode September 14, 2003
Another way to say, Oh boy or Oh my goodness.
Ov vey, you got caught speeding, again.
oy vey by Doss November 11, 2003

oy vas mir 

Yiddish for "Woe is me"

see Oy vey
Oy vas mir, I have to finish that paper for tomorrow and I thought it was for next week !
oy vas mir by Sylvain July 21, 2004
1 used when frustrated
2 Used when anoyed by other people fighting or arguing and it becomes a big mess
3 used when you dont want to do something like wake up in the morning becuase you think its too early
1 OY VAY!!!!
2 oy vay ... this isnt working
3 Oy vay its only 6:00. or oy vay i have so much to do today.