Sis

A sexual nickname used by gang members

Hey sis

by Gang guy 254 October 14, 2016

Sis

A perfect response to your friend saying something stupid, bitchy, slutty or just something u can't think of a reply to

Person 1: Idk which guy to meet this weekend, there's a choice of 3
Person 2: sis

by Theteakeeper January 12, 2019

IUD SIS / SIS IUD

This is an acronym from the Peaches Song "Fuck the Pain Away." While "SIS" probably does stand for "Stay In School" "IUD" does NOT stand for "Injustice Under Dog" as stated in the other listing for this pair of acronyms. It stands for "Intra-Uterine Device," a free form of birth control provided by Planned Parenthood. Peaches is encouraging girls to stay in school by not getting pregnant.

"IUD SIS / SIS IUD... stay in school cause it's the best."

by morebettermostrighter January 9, 2010

sis

an incredibly annoying yet popular term used mainly by teenage girls. “sis” or “sister” originated from the popular yet toxic youtuber james charles. the word usually replaces someone’s name in a phrase, and it not meant to be offensive for the most part. can be used rudely though, as seen in example 2. word for the wise, try to keep the number of times you use this word a day to 0.

ex 1: “omg! spill the tea sis!!”
ex 2: “don’t even go there sis, you look like a rat.”

by riley0 March 29, 2019

si

Abriviation for suck it, normally used on MMORPG's to make fun of the loser.

Oh, man! Did you just see that head shot? Bet you didnt see that coming loser! SI n00b! Better luck next time!

by Nicholson L. May 17, 2006

Si

SI : meaning ha ha ha(in a sarcastic tone)or your not very smart
randomly made up on the spot because someone mispelt my name so i said si (because that was the bit they missed out) he said "what?" so i carried on saying si just to make him feel like he'd missed out on something. now it is a word! i hope:)

someone makes a joke about you thats not very funny you say "si si"
OR
someone answers a question wrong you say "si" and laugh

by Hannah macintosh April 11, 2004

si

VERY sweet, cute, attractive, thoughtful, smart, funny young woman found in and around the London area. Keep your eyes peeled but dont touch, she's already claimed ;)

Just think of someone that fits the description above - there's only one person you can think of!

by shiftkis May 16, 2003