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Mainlining

The act of binge-watching or binge-listening all episodes of a podcast or all episodes in a season of a TV show without breaking for sleep.
Mackey: Where were you last night?
Buddy: Aw, man, I was mainlining "Sense8." After the second episode, I was addicted!
Mainlining by GypsyBowl July 20, 2015

mainlining

the act of taking internet lingo and applying it to real life conversation
matt: I walked by a group of kids taking a test and said, "fucking scrubs."
joel: dude, you were totally mainlining.
mainlining by Taxt April 17, 2009

mainlining

pursuing (somone, something) with an intensity that keeps you up from Page Zero to Page Zero
Jasper and Kelsey stayed up all night mainlining after a good acronym for the pres search
mainlining by thresky October 21, 2022

Mainlining

The act of participating in a traditional conga line, however everyone must insert their penis into the next man’s anus. There must be at least 10 people for this to count. Extra points if the front of the conga line meets the back to form a circle. This continues for at least 45 minutes before simultaneous ejaculation. Everyone then shits themselves, whilst still having a penis in their rear. The ritual ends with post ejaculation docking.
Fin: I really want to go mainlining with the lads
Alfie: me too
Mainlining by Crack the whipper March 13, 2025

Mainlining Murder

A killing in which drugs are shot into the veins. Used in the song by Lars Frederiksen and the Bastards
I said a mainlining murder baby (part of the lyrics)

maingaining 

Maingaining is eating at your maintenance calories or near maintenance, so as to minimize fat gain while still gaining muscle. It is a consistent and steady health focused method of gaining muscle, popularized largely by Greg Doucette.
"Hey man are you bulking or cutting right now?"

"Neither, I am maingaining. I am tired of bulking and cutting cycles."
maingaining by Baratel January 26, 2021