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(Also Shisno) Is a word used by the character Gary from Red vs Blue. It is the excrement of the defecation of a foul-smelling animal. It is also an insult (i think) for the human race.
Gary: Andy and I are not on speaking terms right now. He is kind of jerk.
Andy: Im not the jerk, your the jerk, jerk.
Gary: That was kind of rude.
Andy: Ah shut up you shizno!

yes i copy-pasted the example done by sam, wanna fight about it?
Related Words
a shizno is a smelly animal who's excremeant produces it's own defication: often used as a insult
look what you did to my shirt you damn shizno!
shizno by flaminshiz April 16, 2007
The essence of being dirty and idiotic. Shizno's usually are able to go beyond the normal limits of human stupidity.
shizno by John Dunbar November 15, 2006
One who stupid, or is performing stupid acts.
Dude you're such a shizno.
"dumbass"
shizno by Xander^Cage July 18, 2006
Something/someone who is concidered "cool" or "great". Can also be used as an exclimation. Not to be confused with Shizni.
"Free pancakes?! Shizno!"
"Yeah that Dick Cheney, is he shizno or what?"
Shizno by Uruloki November 10, 2003

shizno's 

the sandwich restaurant, quizno's in a more gangster word.
Let's go to shizno's to get a sandwich!
shizno's by Rachaellll September 16, 2007