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A pusshole is a vagina, typically a stanky or fishy smelling one. It has a negative connotation.
It smells like dirty pusshole in here!
When a chick gets fucked by a huge dick and her pussy and asshole become one big hole.
Holy shit Denise, that guy I went home with had such a thick dick, I now have a pusshole!
pusshole by Guessume October 10, 2012
i wanna lik ur pusshole
pusshole by HelloFrend February 28, 2018
Somebody who you can't trust, fake-friend

Made popular by Dizzee Rascal
Why you rolling with that pussyole?
Moving with that pussyole?
You know that he’s a pussyole
I showed you he’s a pussyole
He’s always been a pussyole
So he’ll always be a pussyole
But you’re still with that pussyole
You must be a pussyole

Dizzee Rascal - Pussyole (Oldskool)
pussyole by A.D.8 August 19, 2007

pussyhole 

a guy who does not behave like a man.
back of yuh raasclat pussyhole or mi a go bloodclat kill yuh!
pussyhole by pussyfinder July 25, 2003

passhole 

The idiot drivers that move steadily along, but suddenly increase speed when they wake up and realize you are passing them. If they succeed in blocking your opportunity to pass, they will immediately resume the former, annoying pace. If you pass them successfully, they will ride your bumper for a short time before returning to la-la land.
That's right you F%$&!@# passhole. Suddenly you're in a big F%$&!@# hurry!
passhole by Paul Laibach May 1, 2004