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Definitely. From snoopified "for sure". Often used in preceding "my nizzle" as in "for sure, brother".
Q: "Wanna hit dis?"
A: "Fo shizle, my nizzle. Light it up!"
fo shizle by Anonymous April 2, 2003
Related Words

Schizer Tech 

Boring minimal techno or tech house that's absent of any melody, build, hook, or overall character, that electronic elitists consider avant-garde. Usually written or played by hipster douches.
"Wow, that Dj's pants are so tight it think he forgot to mix something into this basic loop."

"No this is his new release. It's called "Fixed Gear Beats" on V-Neck records. It's new age Schizer Tech."
Schizer Tech by 5lo5h March 17, 2011

schized out 

Derived from the word schizo, is mostly related to either paranoia, or having done too many drugs that cannot be handled.

Can also be used when someone is acting irrationally.
1.When I drank some liquor out of my parents cabinet, I got schized out, that they would find some missing.

2. I smoked so much of that heady shit that I got schized out and thought everyone was looking at me... at all the times.

3. One day Jo was all lovey dovey with me, then the next day he schized out and said I was a crazy bitch... yeah I'M the one who's crazy.
schized out by Ima Fox April 28, 2012

Mr. Schiller 

The God of stopping what you're doing, listening, knowing where the door is, hitting yourself on the way out, getting lateslips when you want to go to the washroom, saying the answer is "no." and kay'ing.
Boy: "Excuse me, Mr. Schiller?
Mr. Schiller: "Just stop what you're doing, and listen."
Boy: "I'm not doing anythin-"
Mr. Schiller: "There's the door, don't hit yourself on the way out..."
Boy: "But I didn't do anythin-"
Mr. Schiller: "Get a late slip.."
Boy: "Erm... wha-?"
Mr. Schiller: "I wouldn't say the answer is no, but no."
Boy: "This is ridiculous."
Mr. Schiller: "Kay."
Mr. Schiller by Dureiz March 24, 2011

Fo schizzle my nizzle 

"bro I can hook you up"
"Fo schizzle my nizzle"
"I got you"

schizzle 

for schizzle

for sure
schizzle by rt03 January 21, 2009