off the wagon 

drinking or using drugs after a period of abstinence

I can't believe she is off the wagon after she worked so hard.

off the wagon by Light Joker March 12, 2007

off pissing 

something that pisses you off pissed off

grr that guy is really off pissing!

off pissing by hollie. March 20, 2008

off a bean 

under the influence of prescription drugs in pill form.

some may say this term when someone is acting like they are severely inebriated.

ex. molly, perc

popped a perc im flying off a bean

off a bean by zoont October 30, 2017

Off the knee

Taking something with a grain of salt

I was with my girlfriend and she brought up an ex and I said that’s off the knee

Off the knee by RangerRick21 December 16, 2022

off script 

term used to describe the occasion when one "goes rogue"and acts in a manner not contemplated or planned...

Carl went off script when he stripped to his underwear while at the bar with the guys...

off script by sheila in the car December 30, 2009

Off the perc 

When one is acting in an erratic manner that may be from the lack of an addictive substance.

"Man why are you acting like a crackhead?"
"Sorry bro, I'm off the percs

Off the perc by Hugh_ganus December 30, 2019

off sum 

to be under the influence of drugs or alcohol

Brad: aye bruh did you see that bit from the party the other day that hoe had to be off sum.

off sum by Quann478 May 29, 2021