Mad Cow Disease 

A description for a girl who has a butterface and a bad personality, making her appear as a cow of sorts.

Damn that girl has mad cow disease, she's such an ugly bitch!!!

Mad Cow Disease by CheefQueefQueens69 May 12, 2022

Mad Cow Disease 

A legitimate medical term for the symptoms of P.M.S.

A woman with Mad Cow Disease is referred to as a mad cow.

Matt, "Thanks for taking me to the indian casino to play poker tonight. I had to get the fuck away from my wife before she drove me nuts."

Jeff, "You're welcome. I knew you needed it. According to my calender she's got mad cow disease this week."

Mad Cow Disease by dooshkanew August 23, 2009

mad cow powder 

Ketamine Hydrochloride. So called because it induces a stupour in users not dissimilar to mad cow disease.

mad cow powder by Anonymous May 26, 2003

Mad Cow disease 

Feeding a cow animal by-product resulting in giving the cow serious constipation therefore having an angry cow.:{

The cow looks mad he must have that mad cow disease he has'nt shat for a Week

Mad Cow disease by Triple D May 6, 2005

Mad Cow Disease 

your mother mid cycle

your mother during a heavy flow finding she has no sanitary towels in the house

Mad Cow Disease by ulrich von lichtenstein February 5, 2004

mad cow disease 

what guys have when they don't want to or aren't willing to get rid of their ex girlfriends after already moving on to a new one.

that guy has some serious mad cow disease

mad cow disease by xxxYOLIxxx July 9, 2007

Mad Cow Disease 

another way to say PMS

Why is PMS called PMS? Because mad cow disease was already taken

Mad Cow Disease by Blair* December 28, 2005