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AD refers to alcoholism and depression. Some people have one or the other, but in more severe cases some people may have both.

In the case of such an event the proper way to refer to the condition is AD or “the good ole AD combo”
“Bro, did you hear about what Chad did last night?”
“No, what happened?”
“He was drunk af and got kicked out of the bar for asking the bouncer for cocaine. then said he was going to wrap him and his car around a tree”
“Fuck, sounds like he has a pretty bad case of the good ole AD”
AD by Boopsperminute October 15, 2019
Related Words
Adrian Addison adorable adolf hitler Adorkable ADHD adriana addy aditya addie
Also know as advert is an annoying product, website or app that will appear when you are using a website or app. Known for its annoying time of appearance and can really test your patience
Damn it I hate these blumming ads
Ad by Scaryjur12 January 30, 2020
Someone who sees these is a cuck because you don't use an adblocker.
Tim: Hey I saw this Ad
Bob: You saw an Ad in 2020?! What a fucking noob
Ad by Mynameisonelettershor August 25, 2020
"After Donald" as in after the Donald was booted out of the White House and all hope & peace feels plausible. Fun fact: AD era started right during Diwali - the Indian holiday where good "trumps" over evil.
Life is going to be much better in the AD era.
AD by ButtersInLondon November 7, 2020
The individual who people fears most with him and his clique known as OTB
“AD” is the heart of da trap
AD by ADx6 February 17, 2021
OH NO theres an ad again
Ad by laser_fox March 10, 2021