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Comes from the word INDOOR. Unlike outdoor (outdo') endo is Marijuana grown indoors. The term has come to mean better and more potent kind of weed, as the quality of indoor is generally better, although that's not always true...
That wigger said "endo." What a stroke-bag.
endo by dusio February 25, 2008
Evil disease that can't be cured and no-one knows where the hell it comes from. It causes lots of pain and lots of other horrible problems.

Shortened from endometriosis
I can't come in to work today because my endo is so bad i can't walk
ENDO by aurelia April 1, 2003
noun; plural endo, (occasionally) endos

Today there are two popular meanings for the word endo (it's a matter of opinion really):

1.) The first term that was created (which many people still see as still the only correct definition) simply refers to weed that is grown indoors.

2.)Today the term has gained popularity and therefore been a tad manipulated, so endo is also used to describe any decent weed, chronic, or as i like to say, "fuego." This kind of weed typically has red hairs and very visible THC crystals that look like mini jewels.

Manipulation explanation:

Typically the endo is usually better GROWN than the outdo. That's not to say that sunlight isn't the best light out there (or that you couldn't take a crappy outdo seed and make it decent with a little TLC) -- but indoor growers usually grow hydroponically w/ some of the best marijuana-marketed fertilizers out there. Also much outdoor weed is either damaged from shipping across borders, or just from it not being tended too very well -- being that the these aholes usually have fields upon endless fields of the shyt.}
Hey chico you got any of that endo, b/c that duck down the block still got that grimey outdo?
endo by Your future President July 25, 2009
Marijuana. comes from "indoor"
ENDO by bake May 1, 2003
A snowmobile/sled that rides down hill on its front skies.
Yo man bust an endo down that hill
endo by waynejohn186 January 4, 2008
1. Marijuana

2. Endocet - a pill similar to Percocet

3. A bike trick as defined below
1. -

2. eddie took 6 endos and was freaking out.

3. -
endo by Ümbra January 11, 2005