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A gay slang word that refers to using some sort of numbing drug, usually novocaine gel, on a person's rectum to make their first gay, sexual experience less painful or because the active member has a large penis.
Because Teddy is so porno big, he had to give Lamar a "Doopie" so sex wouldn't be too painful for him.
Doopie by TheFinalDoctor August 12, 2017
I got a little DOOPIE IN MY BUTT!
Ew why would you tell me that.
Doopie by Vannnessia May 11, 2021
A sex-neutral term used to connote a child’s genitals. It is sometimes includes the anus.
Don’t forget to wipe your doopie!

Mom, my doopie itches.
Doopie by D00pieSweat June 4, 2021

Doopie Doopie

A person who is slow moving and acts like a real downer. Someone who is negative, unhappy and just plain unpleasant to be around.

Dooping, used as a verb

Antonym: zingy zingy
Don't be such a doopie doopie!
Dave, why you dooping?

Lyndsey, did you doop your pants?
Doopie Doopie by Dr. Zingy November 9, 2018

Doopie Boobie 

A girl with be boobs but lacks hotness
Doopie Boobie by Lil Enslin April 23, 2008

Doopie Doopie

Someone who is not too terribly bright. Intelligent enough to get by, but a space ranger most of the time.
Man. That guy is a real Doopie Doopie! If he had half a brain, he'd be dangerous.
Doopie Doopie by beefymess June 11, 2014