1 definition by TheFinalDoctor
A gay slang word that refers to using some sort of numbing drug, usually novocaine gel, on a person's rectum to make their first gay, sexual experience less painful or because the active member has a large penis.
Because Teddy is so porno big, he had to give Lamar a "Doopie" so sex wouldn't be too painful for him.
by TheFinalDoctor August 12, 2017