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A sex ed program in public school in which teachers who probably haven't actually had sex in about 20 years teach you to keep your hands and other parts to yourself. Sometimes guy will get lucky and have a hot PSI teacher, which makes for an interesting experience.
"Damn, we've got PSI today!"
by Losti March 21, 2005
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When you pretend you dont know someone even though you folow them on twitter this is what you call them
Jake Paul: who is PSI CSI KSI ETC.
by pake paul February 25, 2018
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A hypothetical Covid variant of high consequence first detected in Guatemala. It is showing similar characteristics to the Chi variant such as killing 1 in 5 infected people but it’s also more contagious making it even more dangerous.
by Fortnite1500 November 20, 2021
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psi is pussy fa short and u get psi dere also psi nikkas out dere no gap‰
all yall nikkas psi omm
by kevontis November 21, 2021
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PSI stands for Please Send Info (information)
If you want more information on something just text the person you want to find information from, PSI. This word is a polite way to get info.
Can you PSI on that document from work?
by The_Silly-Goose_13 November 24, 2021
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PSI is short for Pink Shaven Innie. The best type of vagina.
Yad : "My girl has a PSI." Senku : "ZAMN 😍".
by Senku_Willy December 5, 2021
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