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The term Mookie comes from the Spike Lee movie, "Do the Right Thing". There are many definitions of the term Mookie.
The most popular ones are as follows:

1. triflin ass man who is lazy and doesn't take care of his responsibilities, (i.e. his rent payments, his job, HIS KIDS)

2. a fine ass man who looks extremely sexy

3. a term of endearment

4. an adjective to describe a triflin man or woman
1. Damn, Malcolm is such a mookie. Did you know he's a baby daddy and he doesn't pay child support?

2. Oh mah damn, that is one fine lookin man over there, now that's a mookie.

3. Oh mookie, you know I love you.

4. He is being so mookie right now. He fell asleep at work again after he showed up late.
Mookie by Sista Curves & B Money September 21, 2010
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It's not a muffin. It's not a cookie. It'a a mookie.
A muffin made with cookie dough.
I made mookies for all my friends and we threw them a teachers.
Mookie by Melanie January 14, 2004
a derogatory term for just any person. Used to replace the N word
Aw that mookie just robbed me!
Mookie by bojzzle March 10, 2005
Another word for the term Mole which is a bowl of weed and tobacco together smoked out of a bong. Preferably natural American spirit tobacco.
Stoner #1: "I got a little bit of weed let's smoke a bowl bro"
Stoner #2 "I'm only smoking if it's a Mookie"
Stoner #1: "What's a mookie dude?"
Stoner #2: "Another word for a mole bro cmon"
Mookie by Young Yogan December 30, 2016
Used at places like Newtown high school to say you either feel out of it or took too many rips
“Bro you ok?”
Yeah I’m just a little mookie
Mookie by Juulie_Boi May 14, 2019
One who is Boisterous, fearless, and always ready for a fight; not somebody you should mess with
Everybody's scared of her, she fights like a Mookie.
Mookie by Taterm6x February 28, 2014
Someone you can never get over because they just stay there forever and you don't know whether you can ever get over them. You can never tell if you like him or not and it hurts.
I still don't never if I like Mookie or not.