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Screw up 

1. To fail at something, to do something wrong/incorrectly (sometimes repeatedly). Someone that screws up a lot is called a "screw-up"

2. To describe hurting someone emotionally or physically. Commonly used when threatening the one you want to hurt.
1.
Person 1: "I stayed up late last night to study but I couldn't concentrate that well."
Person 2: "You're gonna screw up that test."

"This is the 5th time in a row I'm getting a bad grade. I'm really screwing up."

"I couldn't stop stuttering when introducing myself to him. I screwed up so badly."

2.
"Oh yeah!? You wanna mess with me, kid!? Ohh, I'm gonna SCREW YOU UP!"

Person 1: "Haha, I totally screwed that kid up, did you see his black eye?"
Person 2: "Yeah, he deserved it!"
Screw up by HaltDenMund December 20, 2010

screw up 

The act of failure in doing a job which wasn't intended or expected by the others.
Jim:What the fuck was that man?
Robert:I know I screw up.
Jim:*angry and disappointed*
screw up by dipshite May 12, 2014

Screw up 

A person who does or says something so dumb and screws up friendships
Screw up by Shit friend July 2, 2017

screw up 

Screw up is when you say the wrong name to your bitch while having sex.
uhhh Britney spears, you're so hot - SLAP - My name is Celine dion you stupid motherfucker!
screw up by Kasper Nielsen April 3, 2004

Screw up 

Screw up can be two different things
Ugh I’m such a screw up. :=(
Dang it I just screw up

Although your not so don’t ever say that or else... I’ll call you a turd on repeat!
Screw up by Roseachild:/ April 25, 2020
To make a mess of something, to completely ruin something, to make a mistake
Ffs, what a Screw-Up.
"did you see that? what a Screw-Up!"
Screw-Up by FelixB666XD November 8, 2009